Sugar-Purine Composition for Skin Aging Prevention

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Solution Overview

Problem

Existing skin care compositions containing purine substances do not efficiently utilize their advantageous effects for skin aging prevention and improvement.

Innovation Solution

A composition combining sugar, specifically monosaccharides or disaccharides with at least one unit of glucose, and adenosine phosphate or its salts, where the sugar is present in a proportion of 0.001 to 0.3 parts by weight per part by weight of the purine substance, to enhance intracellular ATP generation and promote skin health.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If purine substances are used in external use compositions for skin aging prevention, then skin cell metabolism is activated and cell turnover is promoted, but the efficiency of utilizing the advantageous effects of purine substances is insufficient

Engineering Contradiction:
Improveefficiency of purine substance utilizationVSAvoideffectiveness of skin aging prevention
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent changes the concentration parameter of purine substances in the composition to optimize their effectiveness. By specifying a particular concentration range of purine substances, the patent achieves more efficient utilization of their skin-benefiting effects while maintaining safety and effectiveness for preventing skin aging.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent creates a composite composition by combining purine substances with other skin care ingredients. This composite formulation enhances the overall effectiveness of purine substances by synergistically combining multiple active components that work together to prevent skin aging, thereby improving the efficiency of purine substance utilization.

Inventive Principle:
Principle #40Composite materials

2Productivity

If the composition promotes ATP generation in cells to accelerate cell turnover, then skin becomes smoother and more resilient, but the water retentivity and softness of skin may be compromised during the acceleration process

Engineering Contradiction:
Improvecell turnover rateVSAvoidskin water retentivity
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent merges multiple functions into a single composition by combining ingredients that promote ATP generation and cell turnover with ingredients that maintain skin hydration. This combination ensures that accelerated cell turnover does not compromise water retentivity, as both functions are simultaneously addressed in the formulation.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent adjusts the concentration parameters of active ingredients to balance cell turnover acceleration with skin hydration maintenance. By optimizing the concentrations of purine substances and hydrating agents, the patent achieves effective cell renewal while preserving skin water retentivity and softness.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition effectively promotes ATP production, leading to improved skin water retentivity, softness, reduced pigmentation, enhanced skin brightness, and accelerated cell turnover, addressing skin aging and dullness effectively.

Implementation Method 1

Purine substances are phosphorylated in a cell and converted into ATP, which serves as an energy source

Methodology Applied
Scientific EffectPhosphorylation: Chemical Bonding

Data Source

PatentEP2238971B1Composition for external application
Publication Date: 2017.09.27 OTSUKA PHARM CO LTD
  • EP2238971B1 patent drawingFigure 1~2

AI summary

The major object of the present invention is to provide a composition for external use capable of more efficiently deriving the effect of purine substances (and/or salts thereof). The present invention provides a composition for external use, comprising (A) sugar; and (B) at least one member selected from the group consisting of purine substances and salts thereof.