Sulfated Lignin for Pathogen Adsorption and Sustainable Hydrogels

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Solution Overview

Problem

Lignin, the second most abundant organic compound on Earth, is underutilized and often discarded as a by-product, lacking effective applications that leverage its valuable properties such as antioxidant, adhesiveness, and antimicrobial properties.

Innovation Solution

Sulfated lignin is repurposed for non-medical uses as an antimicrobial, anti-pathogenic, and anti-spore agent, utilized in hydrogels and sprays for plant protection, water purification, and as a drug carrier, mimicking native mucus to enhance soil health and provide antimicrobial coatings.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Loss of substance

If lignin is used as a by-product without effective applications, then production costs are reduced and resource utilization is improved, but the value of the renewable resource is wasted and environmental impact is increased

Engineering Contradiction:
Improvelignin utilizationVSAvoidenvironmental impact
Core Design Contradiction:
Loss of substanceVSObject-generated harmful factors

Solution Approach 1:

The patent applies chemical modification by sulfating lignin to change its physical and chemical properties, enabling it to function as an effective antimicrobial agent. This parameter change transforms waste lignin into a valuable functional material that can be used in agricultural coatings and plant protection, thereby resolving the contradiction between waste disposal and environmental impact.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent converts the previously harmful waste product (lignin by-product) into a beneficial antimicrobial agent through sulfation. The modified lignin is then applied to plant surfaces and soils to provide protection against pathogens, transforming an environmental burden into a solution for agricultural health and sustainability.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

2Reliability

If synthetic chemicals are used for antimicrobial protection, then effectiveness is achieved, but dependency on synthetic chemicals increases and environmental sustainability decreases

Engineering Contradiction:
Improveantimicrobial effectivenessVSAvoidenvironmental sustainability
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent modifies natural lignin through sulfation to enhance its antimicrobial properties, creating a bio-based alternative to synthetic chemicals. This chemical modification preserves effectiveness while improving environmental sustainability, as the sulfated lignin degrades naturally in the environment unlike synthetic pesticides.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent creates a composite material system combining sulfated lignin with natural carriers or adjuvants to formulate agricultural coatings. This composite approach maintains antimicrobial efficacy while leveraging the biodegradability and environmental compatibility of natural materials, reducing dependency on synthetic chemicals.

Inventive Principle:
Principle #40Composite materials

3Productivity

If sulfated lignin is applied for non-medical uses, then scalability and cost-effectiveness are improved, but medical applications are excluded

Engineering Contradiction:
ImprovescalabilityVSAvoidapplication range
Core Design Contradiction:
ProductivityVSAdaptability or versatility

Solution Approach 1:

The patent develops sulfated lignin formulations that can be applied across multiple non-medical sectors including agriculture, horticulture, and environmental remediation. The universal applicability of the sulfated lignin antimicrobial agent enables scalable deployment in diverse settings while maintaining cost-effectiveness through the use of renewable lignin feedstocks.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Sulfated lignin offers high efficiency in microbial inactivation, environmental sustainability, and scalability, reducing dependency on synthetic chemicals, enhancing soil health, and providing effective antimicrobial and antiviral solutions.

Implementation Method 1

sulfated lignin is used as a compound for adsorbing a microorganism, a pathogen, pollen, and/or spores

Methodology Applied
Scientific EffectAdsorption: Adsorption

Implementation Method 2

Hydrogels are three-dimensional networks of hydrophilic polymers that can absorb and retain large amounts of water

Methodology Applied
Scientific EffectHydrogel formation: Hydrogel

Data Source

PatentEP4609869A1Sulfated lignin for use in pathogen absorption, in water purification, as hydrogel, as medicament, as drug carrier and for mucus replacement
Publication Date: 2025.09.03 FREE UNIV OF BERLIN
  • EP4609869A1 patent drawingFigure 1A
  • EP4609869A1 patent drawingFigure 1B
  • EP4609869A1 patent drawingFigure 2A

AI summary

The present invention relates to novel uses of sulfated lignin, such as its use as compound for adsorbing at least one of a microorganism, a pathogen, pollen, and spores. The invention further relates to a method for preparing a hydrogel comprising sulfated lignin.