Sulforaphane Composition Modulating Lactate for Exercise Adaptation
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Solution Overview
Problem
Current supplements for improving physical exercise performance and adaptation are limited in their ability to effectively modulate lactate and glucose levels, with ketone ester supplementation inducing mild acidosis and disputed performance-enhancing effects.
Innovation Solution
Compositions comprising sulforaphane, glucoraphanin, and myrosinase, such as broccoli sprout juice, which can acutely reduce and chronically increase blood lactate levels, thereby enhancing short-term exercise performance and long-term adaptation to exercise.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If ketone ester supplementation is used to improve exercise performance, then some negative effects during intense exercise are attenuated, but mild acidosis is induced which negates positive effects
Solution Approach 1:
The patent extracts and isolates sulforaphane from its source material (broccoli sprouts) to create a purified supplement that provides the performance-enhancing benefits without the harmful acidosis side effects associated with ketone ester supplementation
Solution Approach 2:
The patent converts the potentially harmful high doses of sulforaphane into a beneficial treatment by demonstrating that controlled supplementation at optimized doses can improve exercise performance and reduce lactate without causing harm
2Object-affected harmful factors
If sulforaphane is administered at high doses to achieve therapeutic effects, then lactate levels are reduced, but side effects may occur
Solution Approach 1:
The patent applies parameter changes by optimizing the dosage of sulforaphane to a specific range (0.03-10 mg/kg body weight) that achieves effective lactate reduction while avoiding the side effects associated with higher doses
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The use of sulforaphane and glucoraphanin compositions significantly improves physical exercise performance by modulating lactate levels, reducing hypoglycemia, and increasing mitochondrial capacity, leading to enhanced endurance and oxidative stress tolerance.
Implementation Method 1
compositions comprising sulforaphane, and/or glucoraphanin and/or myrosinase
Data Source
AI summary
The present invention relates to compositions, uses and methods for improving physical exercise performance, and/or improving adaptation to physical exercise, and/or modulating the concentration of lactate and/or glucose in the blood of a human subject.