Sulforaphane Skincare Composition With On-Demand Precursor Activation

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Solution Overview

Problem

Existing skincare products lack effective utilization of sulforaphane due to its rapid instability and sensitivity to environmental triggers, limiting its use as an antioxidant and anti-inflammatory agent.

Innovation Solution

A skincare composition comprising stabilized glucoraphanin and myrosinase in a powdered form, which reacts with a liquid activator to create sulforaphane upon application, ensuring minimal degradation and optimal potency on the skin surface.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If sulforaphane is directly used in skincare products, then antioxidant and anti-inflammatory benefits are achieved, but the compound rapidly degrades and loses potency due to environmental sensitivity

Engineering Contradiction:
Improvestability of sulforaphaneVSAvoidpotency duration of sulforaphane
Core Design Contradiction:
ReliabilityVSDuration of action of moving object

Solution Approach 1:

The patent divides the unstable sulforaphane molecule into two stable precursor components: glucoraphanin and myrosinase. These segments are separately stabilized and stored, then recombined on-demand to generate active sulforaphane, thereby resolving the contradiction between stability and potency duration.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent performs preliminary stabilization of the precursor components (glucoraphanin and myrosinase) during product formulation, protecting them from degradation. The active sulforaphane is then generated in-situ at the point of use through controlled enzymatic conversion, ensuring both stability during storage and potency when applied.

Inventive Principle:
Principle #10Preliminary action

2Stability of the object's composition

If stabilized precursor components are used instead of direct sulforaphane, then stability and shelf-life are improved, but the product complexity increases due to multiple components and activation requirements

Engineering Contradiction:
Improvestability of skincare compositionVSAvoidcomplexity of product formulation
Core Design Contradiction:
Stability of the object's compositionVSDevice complexity

Solution Approach 1:

The patent employs self-service by incorporating myrosinase enzyme that automatically converts glucoraphanin to sulforaphane upon contact with moisture from the skin or environment. This self-activating mechanism eliminates the need for complex external activation systems, reducing product complexity while maintaining stability.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent uses myrosinase as an intermediary substance that mediates the conversion between stable glucoraphanin and active sulforaphane. This intermediary enables controlled generation of the active compound without requiring complex formulation techniques, thereby improving stability while managing product complexity.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Object-affected harmful factors

If sulforaphane is applied topically to achieve anti-aging benefits, then skin protection is enhanced, but the compound degrades before penetrating and acting on the skin surface

Engineering Contradiction:
Improveprotection against environmental stressorsVSAvoidtime for sulforaphane to act on skin
Core Design Contradiction:
Object-affected harmful factorsVSLoss of time

Solution Approach 1:

The patent performs preliminary stabilization of precursor components in the formulation, ensuring they remain intact during storage and application. The active sulforaphane is then generated in-situ at the moment of skin contact, eliminating the time loss associated with transporting and stabilizing pre-formed sulforaphane to the skin surface.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent extracts the unstable sulforaphane from the final formulation and replaces it with stable precursors that generate sulforaphane in-situ at the application site. This extraction of the problematic compound while retaining its function through precursor conversion resolves the time loss issue by generating the active ingredient exactly when and where it is needed.

Inventive Principle:
Principle #2Taking out (Extraction)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition effectively delivers sulforaphane to the skin, providing potent antioxidant and anti-inflammatory benefits, enhancing skin health and stability through controlled activation.

Implementation Method 1

the predetermined amount of the one or more cruciferous vegetables including stabilized glucoraphanin and active myrosinase in a stable state; wherein exposing the powdered substance to a liquid activator causes a chemical reaction between the stabilized glucoraphanin and the active myrosinase to create sulforaphane

Methodology Applied
Scientific EffectEnzyme catalysis: Enzyme

Implementation Method 2

causes a chemical reaction between the stabilized glucoraphanin and the active myrosinase to create sulforaphane

Methodology Applied
Scientific EffectHydrolysis: Hydrolysis

Data Source

PatentUS12611373B2Skincare composition and process for creating sulforaphane
Publication Date: 2026.04.28 COPELAND AMBER
  • US12611373B2 patent drawing
  • US12611373B2 patent drawing
  • US12611373B2 patent drawing

AI summary

A skincare composition includes a substance having a predetermined amount of one or more cruciferous vegetables, the predetermined amount of the one or more cruciferous vegetables including stabilized glucoraphanin and active myrosinase in a stable state; exposing the substance to a liquid activator causes a chemical reaction between the stabilized glucoraphanin and the active myrosinase to create sulforaphane in an active product; and applying the activated product to a skin surface allows the sulforaphane to act upon the skin surface.