Sunscreen Compositions With Neutral Core Human Milk Oligosaccharides

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Solution Overview

Problem

There is a challenge in increasing the sun protection factor (SPF) of sunscreen compositions due to the limited availability of approved sunscreen active agents, necessitating the use of natural ingredients that can enhance SPF.

Innovation Solution

Incorporating neutral core human milk oligosaccharides, such as Lacto-N-Tetraose and Lacto-N-Neotetraose, into sunscreen compositions to significantly increase SPF.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If the amount of approved sunscreen active agents is increased to achieve higher SPF, then sun protection factor improves, but the availability and variety of approved agents is limited

Engineering Contradiction:

Improvesun protection factorVSAvoidavailability of approved agents

Core Design Contradiction:

ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent introduces neutral core human milk oligosaccharides as an intermediary substance that enhances the SPF of existing sunscreen active agents without requiring approval as a new active agent itself. These oligosaccharides act as mediators that amplify the protective effect of conventional agents, allowing higher SPF achievement within the existing regulatory framework.

Inventive Principle:

Principle #24Intermediary (Mediator)

Solution Approach 2:

The invention creates a composite sunscreen system by combining conventional sunscreen active agents with neutral core human milk oligosaccharides. This composite approach leverages the synergistic effect between the two components, where the oligosaccharides enhance the UV protection capability of the traditional agents, thereby achieving higher SPF with a diversified formulation.

Inventive Principle:

Principle #40Composite materials

2Adaptability or versatility

If natural ingredients are used to increase SPF, then availability of agents improves, but the effectiveness and reliability of SPF enhancement must be verified

Engineering Contradiction:

Improveavailability of natural ingredientsVSAvoidSPF enhancement effectiveness

Core Design Contradiction:

Adaptability or versatilityVSReliability

Solution Approach 1:

The patent systematically varies the concentration of neutral core human milk oligosaccharides in the sunscreen formulation to optimize SPF enhancement. By adjusting the amount of oligosaccharide added, the invention demonstrates a dose-dependent increase in SPF, thereby establishing reliable effectiveness while utilizing naturally occurring ingredients.

Inventive Principle:

Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The addition of these oligosaccharides enhances SPF by at least 20% to 100%, providing effective protection against UV radiation.

Implementation Method 1

certain human milk oligosaccharides namely the neutral core human milk oligosaccharides composed of galactose, N-acetylglucosamine, and glucose monosaccharide such as Lacto-N-Tetraose (LNT) or Lacto-N-Neotetraose (LNnT) are able to significantly increase the SPF of a composition comprising at least one sunscreen active ingredient

Methodology Applied

Scientific EffectUV radiation absorption: Absorption (EM radiation)

Data Source

PatentUS20250325466A1Novel compositions

Publication Date: 2025.10.23 DSM IP ASSETS BV

AI summary

The present invention relates to compositions containing at least one sunscreen active agent and having improved sun protection factor (SPF) properties, as well as methods of improving sun protection factor (SPF) properties.