Self-Powered Glucose Sensor Using Supercapacitor and Microneedle Array

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Solution Overview

Problem

Conventional continuous glucose monitoring devices face issues with device lifespan due to the need for external power, discomfort, and inaccurate glucose measurement, especially in young diabetes patients, and struggle to monitor glucose changes in real time.

Innovation Solution

A glucose sensor with a microneedle array, enzyme layer, and integrated supercapacitor that stores charge generated by glucose oxidation, allowing for self-powered operation, high accuracy, and real-time glucose monitoring without external power, using a wireless communication module for data transmission.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If a conventional continuous glucose monitoring device measures glucose by detecting tissue fluid movement through capillary action, then glucose can be measured continuously, but a time difference occurs in the reflection of glucose

Engineering Contradiction:
Improvecontinuous glucose measurement capabilityVSAvoidglucose reflection timing accuracy
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The device is segmented into multiple microneedles (array of 3-10 microneedles) that penetrate the skin to directly access tissue fluid, eliminating the need for capillary action and reducing the time delay in glucose detection

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The invention transitions from surface-level capillary action to subsurface microneedle penetration, changing the dimensional approach from surface detection to deep tissue fluid access, thereby improving measurement timing accuracy

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Measurement precision

If a conventional glucose sensor applies voltage to measure current during enzyme reaction, then glucose can be measured electrochemically, but the device lifespan is reduced

Engineering Contradiction:
Improveglucose measurement accuracyVSAvoiddevice lifespan
Core Design Contradiction:
Measurement precisionVSDuration of action of stationary object

Solution Approach 1:

The supercapacitor serves itself by storing electrical charge generated from the glucose oxidation reaction, creating a self-powered system that eliminates the need for external voltage sources and extends device lifespan

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The invention replaces the conventional electrochemical current measurement system with a voltage measurement system using a supercapacitor, substituting the need for continuous external power with a self-charging mechanism

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Loss of information

If a wireless communication device is added to transmit glucose signals, then glucose data can be recorded externally, but tens of microwatts of power are consumed per measurement

Engineering Contradiction:
Improveglucose data transmission capabilityVSAvoidpower consumption
Core Design Contradiction:
Loss of informationVSUse of energy by moving object

Solution Approach 1:

The wireless communication module is merged with the supercapacitor power system, allowing the supercapacitor to simultaneously power both the glucose sensing and wireless transmission functions, optimizing energy utilization

Inventive Principle:
Principle #5Merging (Combining)

4Ease of operation

If glucose is measured by detecting light intensity from a light emitting unit, then glucose information can be determined, but accuracy is low and measured information cannot be recorded

Engineering Contradiction:
Improveglucose detection simplicityVSAvoidglucose measurement accuracy
Core Design Contradiction:
Ease of operationVSMeasurement precision

Solution Approach 1:

The invention replaces the optical detection system with an electrical voltage measurement system using a supercapacitor, substituting light intensity detection with electrical charge measurement to improve accuracy and enable data recording

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution extends device lifespan, reduces user discomfort, and enables precise, real-time glucose monitoring with high accuracy, improving power efficiency and convenience.

Implementation Method 1

a charge generated by oxidation of glucose in the enzyme layer may be stored in the supercapacitor

Methodology Applied
Scientific EffectOxidation: Oxidation

Implementation Method 2

as glucose is measured due to tissue fluid moving from the surface of a needle inserted into the skin to the inside of the sensor due to capillary action

Methodology Applied
Scientific EffectCapillary action: Capillary Action

Implementation Method 3

a supercapacitor located on the other side of the flat part

Methodology Applied
Scientific EffectCapacitance: Capacitance

Data Source

PatentUS20240415416A1Glucose monitoring sensor of voltage measurement type including a supercapacitor and a continuous measurement method of glucose using the same
Publication Date: 2024.12.19 IND ACADEMIC COOP FOUND YONSEI UNIV
  • US20240415416A1 patent drawing
  • US20240415416A1 patent drawing
  • US20240415416A1 patent drawing

AI summary

A voltage measurement type glucose sensor comprises a microneedle array including a flat part and a plurality of microneedles located on one surface of the flat part; an enzyme layer located on a surface of the plurality of microneedles and including glucose oxidase; a supercapacitor located on the other side of the flat part; and a wireless communication module electrically connected to the supercapacitor, and a glucose measurement method using the same. The glucose sensor is self-driving without the need to apply separate external power, improving the lifespan of the device and enabling close monitoring of accurate glucose levels in real time,