Superparamagnetic Nanoparticle Laminate for Induction Heating

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Solution Overview

Problem

Existing therapeutic systems face challenges in controlling temperature for effective active ingredient delivery through the skin, as they rely on contact heat or infrared radiation, which can be uneven and poorly controllable due to surface irregularities and distance variations.

Innovation Solution

Incorporating superparamagnetic nanoparticles into the therapeutic system's laminate layers, which are actuated by an electrically controlled induction system generating a time-varying magnetic field, allowing for targeted heating and enhanced active ingredient diffusion.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Temperature

If contact heat transfer is used to heat the therapeutic system, then heat can be transferred to the system, but unevenness or interruptions in the contact surface lead to disruptions in heat transfer and poor controllability

Engineering Contradiction:
Improvetemperature controlVSAvoidheat transfer stability
Core Design Contradiction:
TemperatureVSReliability

Solution Approach 1:

The patent replaces the mechanical contact-based heating system with an electromagnetic induction heating system. The induction system uses a time-varying magnetic field to induce eddy currents in the therapeutic system, which generates heat internally through resistive heating. This eliminates the need for direct thermal contact and its associated problems with surface unevenness and heat transfer instability.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent employs periodic alternating current to generate a time-varying magnetic field that penetrates the therapeutic system. This periodic electromagnetic action induces continuous eddy currents in the conductive therapeutic system, enabling controlled and uniform heating without relying on unstable thermal contact.

Inventive Principle:
Principle #19Periodic action

2Temperature

If infrared radiation is used for heat transfer, then heat can be transferred without contact, but the amount of heat transferred depends on distance and angle, leading to uneven and poorly controllable heat supply

Engineering Contradiction:
Improvetemperature controlVSAvoidheat supply controllability
Core Design Contradiction:
TemperatureVSEase of operation

Solution Approach 1:

The patent replaces infrared radiation heating with electromagnetic induction heating. Instead of using radiant heat that is sensitive to distance and angle variations, the system uses a time-varying magnetic field that induces eddy currents directly in the therapeutic system, providing more predictable and controllable heating that is less sensitive to positioning variations.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent changes the heating mechanism from thermal radiation to electromagnetic induction by utilizing the electrical conductivity of the therapeutic system. By controlling the frequency and amplitude of the alternating current in the induction system, the temperature can be precisely controlled through changes in electrical parameters rather than mechanical positioning parameters.

Inventive Principle:
Principle #35Parameter changes

3Use of energy by moving object

If the therapeutic system requires tight contact with the heat source, then heat transfer efficiency improves, but the device complexity and difficulty of proper application increase

Engineering Contradiction:
Improveheat transfer efficiencyVSAvoidapplication complexity
Core Design Contradiction:
Use of energy by moving objectVSDevice complexity

Solution Approach 1:

The patent replaces contact-dependent thermal heating with non-contact electromagnetic induction heating. The induction system can be positioned near the therapeutic system without requiring tight mechanical contact, as the time-varying magnetic field penetrates through space to induce eddy currents and generate heat within the therapeutic system, thereby simplifying application while maintaining heating efficiency.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This method enables controlled and efficient active ingredient delivery and heat therapy, independent of contact surfaces, with adjustable energy input to optimize diffusion rates and solubility, improving therapeutic efficacy.

Implementation Method 1

at least one laminate layer or an and/or an intermediate layer, arranged between two laminate layers, of the therapeutic system contain(s) superparamagnetic nanoparticles. The electrically actuatable system generates an electric or magnetic field, which varies over time in orientation and magnitude and which penetrates the superparamagnetic nanoparticles.

Methodology Applied
Scientific EffectMagnetic hysteresis heating: Magnetic Hysteresis

Implementation Method 2

The therapy device with this therapeutic system comprises at least one system that can be actuated electrically in a time-varying fashion and is detachably connected to the therapeutic system. The electrically actuatable system generates an electric or magnetic field, which varies over time in orientation and magnitude

Methodology Applied
Scientific EffectElectromagnetic induction: Electromagnetic Induction

Implementation Method 3

a temperature increase in the system leads to an increased diffusion coefficient of the active ingredients in the preparations and hence to an improved active-ingredient delivery

Methodology Applied
Scientific EffectThermal diffusion: Diffusion

Implementation Method 4

increasing the temperature of the system can improve the solubility of active ingredients in the preparation. Thus, a further part of the active ingredient may be dissolved by a temperature increase in the case of formulations that have a component that is an undissolved active ingredient

Methodology Applied
Scientific EffectThermal solubility enhancement: Solvation

Data Source

PatentUS9320720B2Controllable therapeutic system
Publication Date: 2016.04.26 LTS LOHMANN THERAPIE SYST AG
  • US9320720B2 patent drawing
  • US9320720B2 patent drawing
  • US9320720B2 patent drawing

AI summary

A therapeutic system, designed as a laminate and including at least one adhesive laminate layer is described. Also described is a therapeutic device having such a therapeutic system. For this purpose, at least one laminate layer or one intermediate layer and/or one intermediate layer arranged between two laminate layers contains superparamagnetic nanoparticles. The therapeutic device having such a therapeutic system includes at least one electrically controllable system which is detachably connected to the therapeutic system. The electrically controllable system has a frequency-dependent electric resistance. During operation of the therapeutic device, the electrically controllable system generates an electric or magnetic field, which can be varied in orientation and intensity over time and penetrates the superparamagnetic nanoparticles. This provides a controllable therapeutic system that is independent of contact surfaces, and a therapeutic device having such a controllable therapeutic system.