Synergistic Supplement Formulation for Skin Protection

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Solution Overview

Problem

Current skincare products fail to address the underlying causes of skin damage such as oxidative stress and glycation, and are not tailored to individual skin types, leading to inadequate protection and repair.

Innovation Solution

A composition and method of treatment using a supplement formulation comprising medium-chain triglycerides, amino acids, and cannabinoids, specifically caprylic acid, L-carnitine fumarate, and cannabidiol, applied transdermally or orally to enhance skin protection and repair.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Object-affected harmful factors

If topical UV-blocking agents and oils are applied to protect skin, then skin protection against environmental damage is improved, but the underlying causes of skin damage such as oxidative stress and glycation are not addressed

Engineering Contradiction:
Improveskin protectionVSAvoideffectiveness of treatment
Core Design Contradiction:
Object-affected harmful factorsVSReliability

Solution Approach 1:

The patent introduces intermediary substances (antioxidants, anti-glycation agents) that mediate between the harmful environmental factors and skin cells. These compounds act as mediators that neutralize oxidative stress and glycation processes, addressing the root causes rather than just blocking external factors.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent extracts and addresses the specific harmful mechanisms (oxidative stress, glycation) separately from general environmental protection. By identifying and targeting these specific pathological processes with dedicated active ingredients, the treatment addresses underlying causes rather than merely preventing external damage.

Inventive Principle:
Principle #2Taking out (Extraction)

2Device complexity

If single-ingredient supplements are used, then the formulation is simple, but the penetration and absorption are insufficient compared to multi-ingredient combinations

Engineering Contradiction:
Improveformulation complexityVSAvoidpenetration and absorption
Core Design Contradiction:
Device complexityVSReliability

Solution Approach 1:

The patent merges multiple active ingredients with different functions (antioxidants, anti-glycation agents, anti-inflammatory compounds) into a single synergistic formulation. This combination approach leverages the complementary mechanisms of action to achieve enhanced penetration and absorption while addressing multiple pathological pathways simultaneously.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent creates a composite supplement formulation containing diverse bioactive compounds that work together synergistically. This composite approach combines substances with varying molecular properties to optimize both penetration through skin barriers and absorption into target tissues, achieving superior efficacy compared to single-ingredient approaches.

Inventive Principle:
Principle #40Composite materials

3Ease of manufacture

If skincare products are designed for general use, then they are easy to manufacture, but they fail to address individual skin type variations and specific damage mechanisms

Engineering Contradiction:
Improveproduct manufacturingVSAvoidtailoring to skin types
Core Design Contradiction:
Ease of manufactureVSAdaptability or versatility

Solution Approach 1:

The patent applies the principle of local quality by providing different formulations tailored to specific skin types and conditions. Rather than a one-size-fits-all approach, the invention offers customized combinations of active ingredients targeted at particular skin concerns (e.g., oxidative stress, glycation, inflammation) and skin types, optimizing efficacy for individual needs.

Inventive Principle:
Principle #3Local quality

Data Source

PatentUS20240408101A1Composition and methods of treatment using synergistically - enhanced supplementation
Publication Date: 2024.12.12 XYGENYX INC
  • US20240408101A1 patent drawing
  • US20240408101A1 patent drawing
  • US20240408101A1 patent drawing

AI summary

A method and compositions of treatment for improving metabolic performance using supplementation, comprising the step of applying a supplement formulation to a human subject via a selected administration route, the supplement formulation comprising therapeutically effective amounts of a plurality of medium-chain triglycerides, a plurality of amino acids, a plurality of cannabinoids, and zeatin. The plurality of medium-chain triglycerides may comprise caprylic acid, the plurality of amino acids may comprise carnitine which may be provided in the form of L-carnitine fumarate, and the plurality of cannabinoids may comprise cannabidiol.