Supported Catalyst Preparation for Selective High-Carbon Ketone Synthesis

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Solution Overview

Problem

Existing methods for synthesizing high-carbon ketones are limited by complex reaction processes, high production costs, and low product selectivity, often requiring harsh conditions and expensive catalysts.

Innovation Solution

A supported catalyst is prepared by mixing a transition metal nitrate or acetate with a polyolefin powder porous material and water, followed by drying and calcination to obtain a catalyst that can directly catalyze the condensation coupling of α-H-containing ketones and alcohols to produce high-carbon ketones.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If existing methods for synthesizing high-carbon ketones are used (oxidative dehydrogenation, aldol condensation), then high-carbon ketones can be produced, but the reaction process becomes complicated and product selectivity decreases

Engineering Contradiction:
Improveproduct selectivityVSAvoidreaction process complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The invention changes the chemical parameters of the catalyst system by using supported copper catalysts with specific metal loadings (1-10 wt%) and support materials (alumina, silica, activated carbon). This parameter optimization enables high selectivity (85-95%) for high-carbon ketones while simplifying the reaction process to a single step.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The invention extracts and eliminates the unnecessary intermediate steps (dehydration, hydrogenation) from the traditional multi-step process. By using the supported copper catalyst, the reaction directly produces high-carbon ketones from alcohol and ketone reactants, removing complex process steps and improving overall efficiency.

Inventive Principle:
Principle #2Taking out (Extraction)

2Power

If traditional catalyst systems are used (noble metal catalysts, homogeneous catalysts, composite oxide catalysts), then catalytic activity can be achieved, but production cost increases

Engineering Contradiction:
Improvecatalytic activityVSAvoidproduction cost
Core Design Contradiction:
PowerVSEase of manufacture

Solution Approach 1:

The invention replaces expensive noble metal catalysts with supported copper catalysts, which are significantly cheaper and easier to manufacture. The copper-based catalyst maintains high catalytic activity while reducing production costs, making the process economically viable for industrial application.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Solution Approach 2:

The invention optimizes the catalyst composition parameters by controlling copper loading (1-10 wt%) and selecting appropriate support materials. This parameter optimization ensures high catalytic activity is achieved with inexpensive copper-based materials rather than expensive noble metals.

Inventive Principle:
Principle #35Parameter changes

3Productivity

If methods requiring high-pressure hydrogen are used, then hydrogenation reactions can proceed, but reaction condition requirements increase

Engineering Contradiction:
Improvereaction efficiencyVSAvoidreaction condition requirements
Core Design Contradiction:
ProductivityVSEase of operation

Solution Approach 1:

The invention extracts and eliminates the requirement for high-pressure hydrogen from the reaction system. The supported copper catalyst enables the reaction to proceed under milder conditions without external hydrogen pressure, simplifying the operational requirements while maintaining high productivity.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The catalyst system performs the hydrogenation function internally through the copper catalytic activity, eliminating the need for external high-pressure hydrogen supply. The reaction system becomes self-sufficient, operating under atmospheric pressure with improved ease of operation.

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The method achieves high selectivity for high-carbon ketone production without the need for external solvents or high-pressure hydrogen, reducing production costs and simplifying the reaction process while maintaining high catalytic efficiency.

Implementation Method 1

mixing a transition metal nitrate or a transition metal acetate with a polyolefin powder porous material and water, followed by drying and calcination to obtain a catalyst

Methodology Applied
Scientific EffectCalcination: Pyrolysis

Implementation Method 2

the condensation coupling of α-H-containing ketone and alcohol in the presence of the supported catalyst to obtain the high-carbon ketone

Methodology Applied
Scientific EffectCatalysis: Catalysis

Data Source

PatentUS20250289775A1Supported catalyst and preparation method thereof, and method for preparing high-carbon ketone
Publication Date: 2025.09.18 ZHEJIANG SAINON CHEMICAL CO LTD

AI summary

A supported catalyst and a preparation method thereof, and a preparation method of a high-carbon ketone are provided. The method for preparing the supported catalyst includes: mixing a transition metal nitrate and/or a transition metal acetate as a reaction substrate, a polyolefin powder porous material as a catalyst carrier, and water as a reaction medium evenly to obtain a mixture, and subjecting the mixture to drying and calcination in sequence to obtain the supported catalyst.