Surface-Enriched Hemostatic Paste for Faster Bleeding Site Access
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Solution Overview
Problem
Conventional hemostatic agents often have hemostatic agents homogeneously mixed within the paste, which may not be immediately available for hemostatic processes at the bleeding site, potentially leading to delayed hemostasis and unnecessary costs.
Innovation Solution
A bioabsorbable carrier hemostatic material in an elongated form with a supplemental hemostatic agent non-homogeneously distributed, primarily on the surface, allowing faster access to the bleeding site and enhanced hemostatic performance.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Manufacturing precision
If hemostatic agents are homogeneously mixed within the paste, then the paste has uniform composition and structure, but the hemostatic agents are not immediately available for hemostatic processes at the bleeding site, leading to delayed hemostasis
Solution Approach 1:
The patent applies local quality by creating a non-uniform distribution of hemostatic agents within the paste matrix. Specifically, the hemostatic agents are concentrated in the outer region or surface layer of the paste rather than being homogeneously distributed throughout. This allows the agents to be immediately available at the bleeding site when the paste is applied, while maintaining structural integrity of the paste body.
2Ease of manufacture
If hemostatic agents are homogeneously mixed within the paste, then the paste structure is simple and easy to manufacture, but larger quantities of hemostatic agents are required to achieve effective clotting
Solution Approach 1:
By concentrating hemostatic agents in the outer region of the paste, the invention reduces the total quantity of agents needed. The agents are placed where they will have maximum contact with blood upon application, eliminating waste of agents that would be buried deep within the paste and not immediately accessible to the bleeding site.
3Speed
If hemostatic agents are concentrated on the surface, then faster access to the bleeding site is achieved, but the paste structure becomes more complex
Solution Approach 1:
The patent implements local quality through a relatively simple structural modification: concentrating hemostatic agents in the outer region or surface layer of the paste. This creates a layered or zoned structure that is conceptually straightforward - an agent-rich outer region and an agent-poor or agent-free inner region - without requiring complex manufacturing equipment or multi-step processes.
Data Source
AI summary
The present invention is directed to a hemostatic semi-solid paste material comprising a bioabsorbable carrier hemostatic material; and a supplemental hemostatic agent; wherein the paste material has an elongated form extending along a lengthwise axis with an aspect ratio of at least 3; wherein the paste is self-supporting and syringe extrudable; and wherein the supplemental hemostatic agent has a non-homogenous distribution profile across a cross-section taken across the lengthwise axis. In another aspect, the present invention relates to devices for forming and expressing the hemostatic material.