Surface-Guided ROI Determination for Motion-Aware Radiotherapy

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Solution Overview

Problem

Conventional radiation therapy is limited by normal physiological movement, such as respiration or heart movement, which can cause positional movement of the tumor or tissue region undergoing irradiation, leading to inaccuracies in radiation beam sizing and shaping.

Innovation Solution

A method and system that automate the definition of a region-of-interest (ROI) by incorporating geometrical and movement data of the treatment system, using templates and vector fields to register and propagate contour points onto the patient's surface, improving accuracy and calculation speed.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If a user manually defines a region-of-interest (ROI) on a 3D surface image of a patient, then the ROI definition is based on user experience and judgment, but the process is subjective and time-consuming with variable accuracy

Engineering Contradiction:
ImproveROI definition accuracyVSAvoidROI definition time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The system enables automated ROI definition by having the computing device automatically determine the region-of-interest based on treatment information and surface data, eliminating the need for manual user definition while maintaining or improving accuracy through objective algorithms

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The system changes the approach from manual parameter selection to automated parameter determination by processing treatment information, surface data, and registration results to automatically define ROI boundaries and characteristics

Inventive Principle:
Principle #35Parameter changes

2Reliability

If the ROI definition is automated using treatment information and surface data, then the objectivity and consistency of ROI determination is improved, but the system complexity increases

Engineering Contradiction:
ImproveROI definition consistencyVSAvoidautomation system complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The computing device performs multiple functions including obtaining treatment information, acquiring surface data, registering models to surfaces, and automatically determining ROI, consolidating these functions into a single automated system that improves consistency while managing complexity through integration

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The system uses registration models and vector fields as intermediaries to bridge treatment information and surface data, enabling automated ROI determination through systematic processing steps that manage complexity through structured intermediate representations

Inventive Principle:
Principle #24Intermediary (Mediator)

3Manufacturing precision

If the radiation beam is shaped to conform the treatment volume to the exact dimensions of a tumor, then the treatment precision is maximized, but any tumor movement during treatment results in the radiation beam not fully covering the targeted tumoral tissue

Engineering Contradiction:
Improveradiation beam conformanceVSAvoidtreatment coverage reliability
Core Design Contradiction:
Manufacturing precisionVSReliability

Solution Approach 1:

The system performs preliminary actions by automatically defining the ROI based on treatment information and surface registration before treatment delivery, establishing an accurate reference region that accounts for anatomical variations and enables better preparation for motion management

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The automated ROI determination system provides feedback by objectively defining treatment regions based on processed treatment information and surface data, creating a systematic approach that can be consistently applied and monitored throughout treatment delivery

Inventive Principle:
Principle #23Feedback

Data Source

PatentEP4299114B1Methods, systems and computer readable mediums for determining a region-of-interest in surface-guided monitoring
Publication Date: 2026.03.18 SIEMENS HEALTHINEERS INTERNATIONAL AG
  • EP4299114B1 patent drawingFigure 1A
  • EP4299114B1 patent drawingFigure 1B
  • EP4299114B1 patent drawingFigure 2A

AI summary

At least one example embodiment provides a method including obtaining S305 a surface of a patient, obtaining S310 first treatment information for the patient, the first treatment information associated with a treatment for the patient, the first treatment information corresponding to at least one of a treatment intent for the patient, a treatment plan for the patient or a structure of the patient, obtaining S315 at least one model based on the first treatment information for the patient and determining S317 a region of interest of the patient based on the surface of the patient and the at least one model.