Surface-Imprinted Polymer Sensor for Lower Bacterial Detection Limits

The patent applies composite materials by combining synthetic recognition elements with thermal readout platforms in a unified sensing device structure. The recognition element comprises a recognition layer coupled to a substrate, where the recognition layer contains synthetic receptors embedded in a polymer matrix. This composite structure enables the device to simultaneously achieve specific analyte recognition and thermal signal detection, resolving the contradiction between sensitivity and detection accuracy by integrating both functional components synergistically.

The patent applies local quality by incorporating high-thermal-conductivity fillers (such as metal particles, carbon nanotubes, or graphene) selectively into specific regions of the polymer matrix rather than uniformly throughout. The recognition layer contains dispersed filler particles that locally enhance thermal conductivity at the interface where analyte binding occurs, improving detection sensitivity without requiring the entire polymer material to have altered properties. This localized modification maintains the overall stability and compositional integrity of the polymer while achieving the desired thermal enhancement.

The patent applies preliminary action by pre-dispersing carbon-based additives (such as graphene, carbon nanotubes, or metal particles) uniformly throughout the polymer matrix before the recognition layer is formed. The filler particles are incorporated into the polymer during the synthesis or formulation stage, creating a pre-prepared composite material that can be directly applied to the substrate without requiring additional post-processing steps. This preliminary incorporation of additives simplifies the overall manufacturing process while ensuring consistent thermal conductivity enhancement and sensitivity improvement.