Surgical Microscope Fluorescence Overlay Optimization

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Solution Overview

Problem

Current methods for providing image representations in surgical microscopes fail to optimally overlay fluorescence and color images, leading to inadequate detail visibility and contrast, which can obscure vital information during procedures like vascular operations and tumor resections.

Innovation Solution

A method and surgical microscope that process fluorescence images based on application-specific parameters to optimize their overlay with color images, using techniques such as brightness compensation, contrast adjustment, and filtering, to enhance detail visibility and maintain a clear white light impression.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Loss of information

If fluorescence image representation is captured and overlaid with color image representation, then additional information about operation site is provided, but detail visibility and contrast deteriorate

Engineering Contradiction:
Improvefluorescence informationVSAvoiddetail visibility
Core Design Contradiction:
Loss of informationVSMeasurement precision

Solution Approach 1:

The fluorescence image is processed to extract and emphasize only the relevant fluorescent structures (such as blood vessels or tumor tissue) while separating them from the background. This segmentation allows the fluorescent information to be highlighted without overwhelming the overall image details, thus maintaining both information completeness and detail visibility.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Different processing techniques are applied to different regions of the image. In regions where fluorescent structures are present, enhancement techniques are applied to improve contrast and visibility. In regions without fluorescent structures, the original color image is preserved to maintain natural detail and context. This local differentiation optimizes both information presentation and detail preservation.

Inventive Principle:
Principle #3Local quality

2Measurement precision

If fluorescence information is enhanced for better detection, then sensitivity improves, but contrast with surrounding tissue deteriorates

Engineering Contradiction:
Improvefluorescence detection sensitivityVSAvoidcontrast with surrounding tissue
Core Design Contradiction:
Measurement precisionVSIllumination intensity

Solution Approach 1:

The overlay process dynamically adjusts the transparency and intensity of the fluorescence image based on local conditions. In areas with fluorescent structures, the fluorescence signal is enhanced with higher opacity. In areas without fluorescent structures, the color image dominates with higher transparency. This dynamic adjustment maintains optimal contrast throughout the image while preserving detection sensitivity.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

Processing parameters such as brightness, contrast, and opacity are adjusted based on the presence and intensity of fluorescent signals. The system automatically modifies these parameters to enhance fluorescent structure visibility while preventing over-enhancement that would reduce contrast with surrounding tissues. This parameter optimization ensures both sensitive detection and appropriate tissue contrast.

Inventive Principle:
Principle #35Parameter changes

3Adaptability or versatility

If application-specific processing is implemented, then image optimization for specific scenarios improves, but device complexity increases

Engineering Contradiction:
Improveapplication-specific optimizationVSAvoidprocessing system complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The system includes pre-configured processing profiles for common surgical applications (e.g., vascular surgery, tumor resection). These profiles contain predetermined processing parameters and algorithms optimized for each application type. When an application is selected, the corresponding profile is automatically applied, eliminating the need for complex real-time parameter tuning and reducing system complexity while maintaining high adaptability.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

A single processing framework is designed to handle multiple different surgical applications through a unified interface. The system can process different types of fluorescent images (different fluorophores, different wavelengths) and apply different processing algorithms through one versatile platform. This universal approach consolidates what would otherwise require multiple separate systems, reducing overall complexity while maintaining broad adaptability.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach provides an optimized image signal that improves detail perception, allowing for better visualization of structures like blood flow and tumors, reducing errors and enhancing surgical precision by maintaining a clear background and environment visibility.

Implementation Method 1

a fluorescent substance (endogenous or exogenous fluorophore) in the tissue is excited and light emanating from it is captured in a fluorescence image representation

Methodology Applied
Scientific EffectFluorescence: Fluorescence

Data Source

PatentUS20240252276A1Method for providing an image representation by means of a surgical microscope, and surgical microscope
Publication Date: 2024.08.01 CARL ZEISS MEDITEC AG
  • US20240252276A1 patent drawing
  • US20240252276A1 patent drawing
  • US20240252276A1 patent drawing

AI summary

The invention relates to a method for providing an image representation by means of a surgical microscope, comprising obtaining or capturing at least one application parameter, capturing a color image representation of a capture region by means of a camera, capturing a fluorescence image representation of the capture region by means of a fluorescence camera, processing the fluorescence image representation by means of a processing device to optimize it for an overlay with the color image representation, wherein a type of processing is defined based on the at least one application parameter, overlaying the color image representation with the processed fluorescence image representation, and providing an image signal that encodes the overlaid image representation. The invention further relates to a surgical microscope.