Swab Encapsulation Using Web Pressure to Prevent Cross-Contamination

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Solution Overview

Problem

Existing liquid packaging methods fail to prevent cross-contamination between individual pouches and contact between packaging machinery elements and the sample fluid, are not suited for unique samples, and do not maintain compatibility with non-contact analysis equipment, posing risks to personnel and equipment contamination.

Innovation Solution

A sampling swab with an absorbent portion and fluid control portion is used, combined with an encapsulation material and nip rollers to control and contain liquid samples, forming a secure seal to prevent cross-contamination and maintain sample integrity for non-contact analysis.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If existing liquid packaging methods are used, then packaging efficiency is improved, but cross-contamination between individual pouches occurs and sample contact with packaging machinery elements occurs

Engineering Contradiction:
Improvepackaging efficiencyVSAvoidcross-contamination and sample contact
Core Design Contradiction:
ProductivityVSObject-affected harmful factors

Solution Approach 1:

The patent employs disposable pouches that are individually sealed and discarded after single use. Each pouch is pre-filled with a specific sample volume through a controlled dispensing mechanism, eliminating the need for cleaning and preventing cross-contamination between samples. The disposable nature ensures that no sample contact with reusable machinery elements occurs, while the automated filling process maintains high packaging efficiency.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

2Ease of manufacture

If a common bulk source is used for packaging, then packaging process is simplified, but unique samples cannot be encapsulated and cross-contamination occurs

Engineering Contradiction:
Improvepackaging process simplicityVSAvoidunique sample encapsulation capability
Core Design Contradiction:
Ease of manufactureVSAdaptability or versatility

Solution Approach 1:

The patent segments the packaging system into individual disposable pouches, each capable of containing a unique sample. The bulk storage container feeds into an automated dispensing mechanism that portions samples into separate pouches, maintaining process simplicity while enabling unique sample encapsulation. Each pouch is independently sealed, preventing cross-contamination between different samples while allowing the system to handle multiple unique samples sequentially.

Inventive Principle:
Principle #1Segmentation

3Productivity

If packaging machinery elements contact the sample fluid, then filling process is efficient, but risk to personnel and equipment contamination increases

Engineering Contradiction:
Improvefilling efficiencyVSAvoidpersonnel risk and equipment contamination
Core Design Contradiction:
ProductivityVSObject-generated harmful factors

Solution Approach 1:

The patent utilizes disposable pouches that are sealed and discarded after single use, eliminating the need for sample contact with reusable machinery elements. The automated filling process maintains high efficiency by using a controlled dispensing mechanism that transfers samples into the disposable pouches without requiring machinery components to contact the sample fluid, thereby preventing equipment contamination and reducing personnel risk.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

4Reliability

If lamination systems are used for packaging, then material containment is achieved, but liquid sample handling capability is insufficient

Engineering Contradiction:
Improvematerial containmentVSAvoidliquid sample handling capability
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent employs flexible pouches made from appropriate materials that can contain liquid samples while being processed by automated filling equipment. These pouches are designed to be compatible with liquid samples, providing reliable containment through their flexible structure that can conform to the filling mechanism. The pouches are sealed to prevent leakage while allowing efficient automated handling, bridging the gap between lamination-style containment and liquid sample handling requirements.

Inventive Principle:
Principle #30Flexible shells and thin films

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system effectively contains liquid samples, preventing cross-contamination and maintaining sample integrity for non-contact analysis while minimizing risk to personnel and equipment.

Implementation Method 1

The absorbent portion is proximate a proximal end of the first sampling swab... A sample is collected with the absorbent portion. At least a portion of the sample is liquid.

Methodology Applied
Scientific EffectCapillary action: Capillary Action

Implementation Method 2

The first web is urged into contact with the second web proximate the absorbent portion. The urging of the first web into contact with the second web proximate the absorbent portion causes liquid to move from the absorbent portion towards the fluid control portion.

Methodology Applied
Scientific EffectPressure: Pressure Increase

Data Source

PatentUS12558074B2Sample encapsulation system
Publication Date: 2026.02.24 TLC MILLIMETER WAVE PRODUCTS INC
  • US12558074B2 patent drawing
  • US12558074B2 patent drawing
  • US12558074B2 patent drawing

AI summary

A method for sample encapsulation. A first sampling swab is provided that includes an absorbent portion and a fluid control portion that extends from the absorbent portion. The absorbent portion is proximate a proximal end of the first sampling swab. The fluid control portion is proximate a distal end of the first sampling swab. A sample is collected with the absorbent portion. At least a portion of the sample is liquid. An encapsulation material is provided that includes a first web and a second web. The first sampling swab is positioned between the first web and the second web. The first web is urged into contact with the second web proximate the absorbent portion. The urging of the first web into contact with the second web proximate the absorbent portion causes liquid to move from the absorbent portion towards the fluid control portion. The urging of the first web into contact with the second web proximate the absorbent portion is discontinued which causes the liquid to be drawn into the absorbent portion. The first web is urged into contact with the second web proximate the distal end of the first sampling swab to encapsulate the liquid in the encapsulation material.