Swappable Electrode Boards for Digital Microfluidics

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Solution Overview

Problem

Existing digital microfluidics systems are not flexible enough to accommodate various assays, requiring complex and expensive electrode arrays that serve multiple purposes, and lack the ability to easily replace damaged components or adapt to new assays without specialized tools.

Innovation Solution

A digital microfluidics system with swappable electrode boards that can be inserted into the system, allowing for specific electrode arrays to be used for particular assays, and a generic cartridge design that can be used across multiple assays, with the option to replace boards and cartridges without the need for specialized tools.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If a single complex electrode array is used to serve multiple assays, then the system can perform various assays, but the device complexity and manufacturing cost increase

Engineering Contradiction:
Improveassay compatibilityVSAvoidelectrode array complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The electrode array is segmented into multiple interchangeable PCB boards, each designed for specific assay types. Instead of one complex array, the system divides functionality across multiple simpler, specialized boards that can be swapped as needed.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The base unit is designed with universal accommodation sites that can accept different types of electrode PCB boards. The standardized interface allows a single base unit to support multiple assay configurations through board replacement, achieving versatility without increasing individual board complexity.

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Adaptability or versatility

If a single complex electrode array is used to serve multiple assays, then the system can perform various assays, but the manufacturing cost increases

Engineering Contradiction:
Improveassay compatibilityVSAvoidmanufacturing cost
Core Design Contradiction:
Adaptability or versatilityVSEase of manufacture

Solution Approach 1:

The system segments the electrode array into multiple simpler PCB boards that can be manufactured independently using standard manufacturing processes. This reduces the complexity and cost of each individual board while maintaining overall system versatility through board interchangeability.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The electrode PCB boards are designed as disposable or easily replaceable components. Instead of investing in one expensive, complex permanent array, the system uses multiple simpler, lower-cost boards that can be manufactured economically and replaced when needed.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

3Manufacturing precision

If specialized tools are required for replacing components, then precise component replacement is possible, but the ease of operation and repair decreases

Engineering Contradiction:
Improvecomponent alignment precisionVSAvoidcomponent replacement ease
Core Design Contradiction:
Manufacturing precisionVSEase of operation

Solution Approach 1:

The electrode array is segmented into modular PCB boards with standardized connection interfaces. These interfaces are designed to accommodate natural variations in manufacturing tolerances, allowing boards to be replaced by simple insertion and connection without requiring specialized alignment tools or procedures.

Inventive Principle:
Principle #1Segmentation

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach provides flexibility and cost-effectiveness by allowing different assays to be performed using the same system, enabling easy replacement of boards and cartridges, reducing manufacturing costs and allowing for future-proofing of the system.

Implementation Method 1

a central control unit for controlling the selection of individual electrodes of this electrode array and for providing them with individual voltage pulses for manipulating liquid droplets by electrowetting

Methodology Applied
Scientific EffectElectrowetting: Electrowetting

Data Source

PatentUS10724988B2Digital microfluidics system with swappable PCB's
Publication Date: 2020.07.28 TECAN TRADING AG
  • US10724988B2 patent drawing
  • US10724988B2 patent drawing
  • US10724988B2 patent drawing

AI summary

Digital microfluidics system manipulates samples in liquid droplets within disposable cartridges that have bottom layer, top layer, and gap between the bottom and top layers. The system has a base unit with cartridge accommodation sites and a central control unit for controlling selection of individual electrodes of electrode arrays and for providing these electrodes with individual voltage pulses for manipulating liquid droplets within the cartridges by electrowetting. The system further has board accommodation sites located at the cartridge accommodation sites that each can take up a swappable electrode board having an electrode array and electrical board contact elements individually connected to electrodes of the electrode array. Each board accommodation site has electrical base unit contact elements that are connected to the central control unit and that are configured to engage with the electrical board contact elements of a swappable electrode board that is placed at the board accommodation site.