Sweetening Compound Formula I for Rapid Onset and Aftertaste Masking

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Solution Overview

Problem

There is a need for new sweetening compounds and sweet taste enhancers with improved taste and delivery characteristics, as existing high-intensity sweeteners often have undesirable aftertastes and sweetness delivery issues such as delayed onset and lingering sweetness.

Innovation Solution

A compound with the structure of formula (I) or its salt, which can be used in various forms, including isolated and purified forms, in compositions with specific concentrations and combinations, to enhance sweetness in foods and beverages without the drawbacks of existing sweeteners.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If high-intensity sweeteners are used to replace sugar, then sweetness is provided with reduced calories, but undesirable aftertastes and sweetness delivery issues occur

Engineering Contradiction:
Improvecalorie contentVSAvoidundesirable aftertaste
Core Design Contradiction:
Quantity of substanceVSObject-affected harmful factors

Solution Approach 1:

The patent combines multiple sweetening agents including compounds of formula (I), high-intensity sweeteners, and sweet taste enhancers in specific ratios to create a composite sweetening system. This composite approach masks individual aftertastes while maintaining rapid sweetness delivery and reduced calorie content, resolving the contradiction between calorie reduction and aftertaste quality.

Inventive Principle:
Principle #40Composite materials

2Quantity of substance

If existing high-intensity sweeteners are used, then sweetness intensity is increased, but sweetness delivery is delayed and lingering occurs

Engineering Contradiction:
Improvesweetness intensityVSAvoidsweetness delivery time
Core Design Contradiction:
Quantity of substanceVSLoss of time

Solution Approach 1:

The patent employs compounds of formula (I) with specific molecular structures designed to dynamically interact with sweet taste receptors, enabling rapid binding and quick dissociation. This dynamic interaction profile delivers intense sweetness immediately while preventing lingering effects, resolving the time-delay contradiction.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The patent modifies molecular parameters of sweetening compounds including hydrophobicity, molecular weight, and functional group configuration to optimize sweetness delivery kinetics. These parameter changes enable rapid onset and dissipation of sweetness without lingering, while maintaining high intensity.

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS20240108040A1High intensity sweeteners
Publication Date: 2024.04.04 FIRMENICH INC
  • US20240108040A1 patent drawing
  • US20240108040A1 patent drawing
  • US20240108040A1 patent drawing

AI summary

Disclosed herein are compounds having structural Formula (I), or salts thereof. These compounds are useful as sweet tasting agents and/or sweetness enhancers. Also disclosed are compositions comprising the present compounds and methods of increasing the sweet taste of ingestible compositions. Furthermore, methods for preparing the compounds are also disclosed.