SWIR Water-Absorption Sensor for Noninvasive Glucose Detection

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Solution Overview

Problem

Current glucose monitoring methods for diabetes require invasive blood draws, which are painful and inconvenient, and existing non-invasive methods face challenges in sensitivity, selectivity, and repeatability, especially for use in military or emergency settings where finger pricks are dangerous.

Innovation Solution

The use of fiber-based supercontinuum lasers, super-luminescent laser diodes, or light-emitting diodes in the near-infrared spectrum to increase signal levels and reduce spectral artifacts, combined with pattern matching and software techniques for identifying glucose signatures, allowing for non-invasive glucose monitoring through the teeth with less interference from skin artifacts.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Object-affected harmful factors

If non-invasive glucose monitoring methods are used, then patient comfort and safety are improved, but measurement precision and reliability deteriorate

Engineering Contradiction:
Improvepain and risk from invasive proceduresVSAvoidglucose measurement accuracy
Core Design Contradiction:
Object-affected harmful factorsVSMeasurement precision

Solution Approach 1:

The patent uses teeth as an intermediary medium to access glucose in saliva, which then reflects glucose levels in blood. This intermediary approach allows non-invasive monitoring while maintaining measurement accuracy, as the teeth provide a stable, artifact-free optical path compared to direct skin measurement

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent replaces mechanical blood drawing procedures with optical measurement systems that detect glucose through light absorption and reflection. This substitution eliminates the need for invasive mechanical intervention while achieving comparable or superior measurement precision through spectral analysis

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Ease of operation

If skin-based non-invasive glucose monitoring is used, then ease of operation is improved, but measurement precision deteriorates due to spectral artifacts

Engineering Contradiction:
Improveconvenience of monitoringVSAvoidglucose signature detection accuracy
Core Design Contradiction:
Ease of operationVSMeasurement precision

Solution Approach 1:

The patent extracts the measurement site from the skin to the teeth, removing the source of spectral artifacts. By measuring through teeth rather than skin, the system eliminates interfering signals from skin pigmentation, hair, and surface irregularities while maintaining ease of operation through simple oral placement

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent applies local quality by selecting a specific measurement location (teeth) with optimal optical properties for glucose detection. The teeth provide a uniform, translucent medium with minimal spectral artifacts, creating a localized measurement zone that enhances precision without compromising overall system convenience

Inventive Principle:
Principle #3Local quality

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enables non-invasive, accurate, and repeatable glucose monitoring, reducing pain and risk, while also providing a wearable device for wireless data communication and storage, enhancing convenience and safety for individuals with diabetes.

Implementation Method 1

a light source comprising one or more semiconductor diodes that are configured to generate an output optical light having one or more optical wavelengths, wherein at least a portion of the one or more optical wavelengths is a short-wave infrared wavelength between 1400 nanometers and 2500 nanometers

Methodology Applied
Scientific EffectNear-infrared light transmission: Infrared Radiation

Implementation Method 2

deliver at least a portion of the output optical light to an encapsulating layer that is configured to pass at least a portion of the short-wave infrared wavelength

Methodology Applied
Scientific EffectOptical transmission through encapsulating layer: Refraction

Implementation Method 3

a detection system comprising one or more photo-detectors configured to receive at least a portion of the passed output optical light reflected from the tissue or the object

Methodology Applied
Scientific EffectLight reflection: Reflection

Implementation Method 4

a detection wavelength selective optical filter placed between the tissue or the object and the detection system that is configured to transmit at least some of the one or more optical wavelengths

Methodology Applied
Scientific EffectWavelength selective transmission: Filter (optical)

Data Source

PatentUS11896346B2Short-wave infrared sensor for identifying based on water content
Publication Date: 2024.02.13 OMNI MEDSCI INC
  • US11896346B2 patent drawing
  • US11896346B2 patent drawing
  • US11896346B2 patent drawing

AI summary

An optical system operating in the near or short-wave infrared wavelength range identifies an object based on water absorption. The system comprises a light source with modulated light emitting diodes operating at wavelengths near 1090 and 1440 nanometers, corresponding to lower and higher water absorption. The system further comprises one or more wavelength selective filters and a housing that is further coupled to an electrical circuit and a processor. The detection system comprises photodetectors that are synchronized to the light source, and the detection system receives at least a portion of light reflected from the object. The system is configured to identify the object by comparing the reflected light at the first and second wavelength to generate an output value, and then comparing the output value to a threshold. The optical system may be further coupled to a wearable device or a remote sensing system with a time-of-flight sensor.