Switchable Flow Restriction for Isotope Ratio Analyzer Gas Inlet

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Solution Overview

Problem

Current gas inlet systems for isotope ratio analyzers face challenges in minimizing sample loss while maintaining rapid analysis and constant pressure, particularly in continuous flow methods which consume large amounts of samples and suffer from instability issues in stopped-flow techniques.

Innovation Solution

A gas inlet system with a switchable flow restriction allows for controlled gas flow into the isotope ratio analyzer, enabling a higher flow rate for flushing and filling and a lower flow rate for measurement, thereby reducing sample consumption and maintaining constant pressure.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If continuous flow method is used, then rapid analysis is achieved, but large amount of sample is consumed

Engineering Contradiction:
Improveanalysis speedVSAvoidsample consumption
Core Design Contradiction:
ProductivityVSLoss of substance

Solution Approach 1:

The system dynamically switches between high flow rate mode for rapid flushing/filling and low flow rate mode for measurement, allowing the flow rate to adapt to different operational phases rather than maintaining a constant high flow rate throughout

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The system employs periodic switching between different flow rates - high flow rate during flushing and filling phases, then low flow rate during measurement phases - creating a cyclic pattern that optimizes both speed and sample conservation

Inventive Principle:
Principle #19Periodic action

2Loss of substance

If flow rate is reduced to minimize sample consumption, then sample loss is decreased, but response time is increased

Engineering Contradiction:
Improvesample consumptionVSAvoidresponse time
Core Design Contradiction:
Loss of substanceVSLoss of time

Solution Approach 1:

The flow rate is made dynamic rather than static, switching between high and low values based on operational requirements - high flow for rapid cell filling to minimize response time, then low flow for measurement to minimize sample consumption

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The system uses periodic flow rate changes with high flow rate applied during flushing and filling operations to maintain rapid response, then transitions to low flow rate during measurement to reduce sample consumption

Inventive Principle:
Principle #19Periodic action

3Loss of substance

If stopped-flow technique is used, then sample consumption is reduced, but system stability deteriorates due to leaks and pressure changes

Engineering Contradiction:
Improvesample consumptionVSAvoidsystem stability
Core Design Contradiction:
Loss of substanceVSReliability

Solution Approach 1:

The system maintains continuous flow throughout operation rather than stopping, eliminating the stability issues associated with stopped-flow techniques while still achieving low sample consumption during measurement through controlled low flow rate

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The system changes the flow rate parameter dynamically - maintaining continuous flow for stability while adjusting to low flow rate during measurement to achieve both stability and sample conservation

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentEP3088889B1Flow reduction system for isotope ratio measurements
Publication Date: 2020.09.23 THERMO FISHER SCI BREMEN
  • EP3088889B1 patent drawingFigure 1~2
  • EP3088889B1 patent drawingFigure 3

AI summary

A system for controlling flow of gas in a continuous flow isotope ratio analyser is provided. The system comprises gas inlet and gas outlet lines for providing gas into and from a measuring cell, and at least one switchable flow restriction on the gas inlet line, for selectively controlling gas flow into the isotop ratio analyser. Also provided is a method for determining an isotope ratio using the system according to the invention.