Synergistic Active Compound Combinations for Pest Control

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Solution Overview

Problem

Existing active compound combinations for controlling animal and microbial pests, particularly acarids and nematodes, often have unsatisfactory acaricidal and insecticidal efficacy and compatibility with crops, leading to demand for novel combinations with improved properties.

Innovation Solution

A combination of at least one compound of formula (I) with specific IRAC classification group or formula (IIa/IIb) active compounds, or Biological Control Agents, which exhibit synergistic effects, enhancing insecticidal, acaricidal, nematicidal, and plant-strengthening properties.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If existing active compound combinations are used for pest control, then some pest control effect is achieved, but the acaricidal and insecticidal efficacy is not satisfactory

Engineering Contradiction:
Improveacaricidal and insecticidal efficacyVSAvoidpest control effectiveness
Core Design Contradiction:
ReliabilityVSQuantity of substance

Solution Approach 1:

The patent combines compound (I) with compounds of formula (IIa) or (IIb) to create a synergistic mixture that achieves superior acaricidal and insecticidal efficacy. The combination of these specific chemical structures produces an effect greater than the sum of individual components, directly resolving the contradiction between reliable pest control and actual effectiveness.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The invention creates a composite active compound system consisting of compound (I) combined with compounds of formula (IIa) or (IIb). This composite material approach allows the mixture to exhibit enhanced biological activity and synergistic effects, transforming the insufficient efficacy of individual compounds into a highly effective pest control agent.

Inventive Principle:
Principle #40Composite materials

2Reliability

If existing active compound combinations are used, then some pest control is achieved, but compatibility with crop plants is not satisfactory

Engineering Contradiction:
Improvepest control reliabilityVSAvoidcrop plant compatibility
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent modifies the chemical parameters by combining compound (I) with compounds of formula (IIa) or (IIb) in specific ratios and configurations. This parameter optimization achieves a balance where the mixture maintains high pest control reliability while reducing phytotoxicity and improving compatibility with crop plants through controlled compositional changes.

Inventive Principle:
Principle #35Parameter changes

3Ease of operation

If single active compounds are used, then application is simple, but the synergistic effect and overall efficacy are limited

Engineering Contradiction:
Improveapplication simplicityVSAvoidinsecticidal and acaricidal effect
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The patent merges compound (I) with compounds of formula (IIa) or (IIb) into a single combined application formulation. This merging maintains ease of operation by providing a ready-to-use mixture while simultaneously achieving superior synergistic insecticidal and acaricidal effects that neither compound could achieve alone.

Inventive Principle:
Principle #5Merging (Combining)

Data Source

PatentUS11819025B2Active compound combinations having insecticidal/acaricidal properties
Publication Date: 2023.11.21 BAYER AG
  • US11819025B2 patent drawing
  • US11819025B2 patent drawing
  • US11819025B2 patent drawing

AI summary

The present invention relates to novel active compound combinations comprising at least one known compound of the formula (I) and at least one further active compound, which combinations are highly suitable for controlling animal and microbial pests such as unwanted insects and/or unwanted acarids and/or unwanted nematodes.