Synergistic Active Compound Combinations for Pest Control
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Solution Overview
Problem
Current active compound combinations for controlling animal and microbial pests, particularly acarids and nematodes, often have unsatisfactory acaricidal and insecticidal efficacy and compatibility with crops, leading to a demand for novel formulations with improved properties.
Innovation Solution
A combination of compounds of formula (I) and active compounds from IRAC classification group (28) or specific compounds of formulas (IIa, IIb, IIc, or IId), which exhibit a synergistic effect when used together, enhancing insecticidal, acaricidal, nematicidal, and plant-strengthening properties.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If known compounds for pest control are used, then basic insecticidal activity is achieved, but acaricidal and insecticidal efficacy is not satisfactory
Solution Approach 1:
The patent combines compound (I) with active compounds from IRAC group (28) or formulas (IIa-IIc) to create synergistic combinations. This merging of different chemical entities with distinct modes of action resolves the contradiction by achieving both satisfactory acaricidal efficacy (through compound I) and enhanced insecticidal activity (through the combination partners), thereby improving overall pest control effectiveness beyond what single compounds can achieve.
2Reliability
If known compounds are used, then some pest control activity is achieved, but compatibility with crop plants is not satisfactory
Solution Approach 1:
The patent modifies the chemical parameters by combining compound (I) with specific active compounds from IRAC group (28) or formulas (IIa-IIc) at optimized ratios. This parameter change in composition creates a synergistic effect that maintains or enhances pest control activity while reducing individual compound doses, thereby improving crop plant compatibility and reducing phytotoxicity.
3Ease of operation
If single active compounds are used, then simplified application is achieved, but synergistic effect is not realized
Solution Approach 1:
The patent merges compound (I) with active compounds from IRAC group (28) or formulas (IIa-IIc) into pre-mixed formulations with optimized ratios. This merging maintains ease of operation by providing ready-to-use combinations while realizing synergistic effects that enhance reliability and efficacy beyond what single compounds can achieve, eliminating the need for separate application of multiple compounds.
Data Source
AI summary
The present invention relates to novel active compound combinations comprising at least one known compound of the formula (I)and at least one further active compound, which combinations are highly suitable for controlling animal and microbial pests such as unwanted insects and/or unwanted acarids and/or unwanted nematodes.