Synergistic Microbicidal Composition Using Nonionic Surfactant and MIT
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Solution Overview
Problem
Current microbicidal compositions lack synergistic activity against various microorganism strains and often require high levels of individual microbicides, posing environmental and economic challenges.
Innovation Solution
A synergistic microbicidal composition comprising a nonionic surfactant with specific structures and 2-methyl-4-isothiazolin-3-one, with weight ratios optimized to minimize 5-chloro-2-methyl-4-isothiazolin-3-one content, effectively inhibiting microorganism growth in aqueous media.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If higher levels of individual microbicides are used, then microorganism growth control is improved, but environmental harm and cost increase
Solution Approach 1:
The patent combines two different microbicides (2-methyl-4-isothiazolin-3-one and a nonionic surfactant) into a single composition that produces synergistic effects. This merging allows achieving superior microorganism growth control at lower individual concentrations of each microbicide, thereby reducing environmental harm while maintaining or improving efficacy.
Solution Approach 2:
The invention creates a composite microbicidal composition by formulating 2-methyl-4-isothiazolin-3-one with specific nonionic surfactants. This composite approach leverages the complementary properties of both components to achieve enhanced antimicrobial activity against bacteria, yeast, and mold at reduced concentrations, addressing both efficacy and environmental concerns.
2Reliability
If higher levels of individual microbicides are used, then microorganism growth control is improved, but cost increases
Solution Approach 1:
By merging 2-methyl-4-isothiazolin-3-one with nonionic surfactants in a synergistic formulation, the patent achieves improved microorganism growth control using lower quantities of each active ingredient. This reduces the overall cost of the composition compared to using higher concentrations of single microbicides.
Solution Approach 2:
The invention changes the concentration parameters of the microbicides by utilizing lower levels of 2-methyl-4-isothiazolin-3-one and nonionic surfactant in combination, rather than relying on high concentrations of individual microbicides. This parameter optimization reduces material costs while maintaining or enhancing efficacy.
3Reliability
If conventional microbicidal compositions are used, then microorganism control is achieved, but synergistic activity against various microorganism strains is lacking
Solution Approach 1:
The patent develops a composite formulation combining 2-methyl-4-isothiazolin-3-one with multiple types of nonionic surfactants (polyethylene glycol alkyl ethers, polyoxyethylene sorbitan esters, and alkyl polyglycosides). This composite structure provides broad-spectrum synergistic activity against bacteria, yeast, and mold, enhancing adaptability across various microorganism strains while maintaining effective control.
Solution Approach 2:
The formulated composition achieves multi-functionality by demonstrating effective synergistic activity against diverse microorganism types including bacteria, yeast, and mold. The combination of 2-methyl-4-isothiazolin-3-one with different classes of nonionic surfactants creates a universal microbicidal agent that adapts to control various strains across different applications.
Data Source
AI summary
A synergistic microbicidal composition having two components. The first component is a nonionic surfactant with structure: R1O(CH2CH(CH3)O)5(CH2CH2O)9H, where R1 is a C8alkyl group. The second component is 2-methyl-4-isothiazolin-3-one. The weight ratio of the nonionic surfactant to 2-methyl-4-isothiazolin-3-one is from 1:0.005 to 1:1.3714. Alternatively, the first component is a nonionic surfactant with structure: R2O(CH2CH(CH3)O)3(CH2CH2O)7H, where R2 is a mixture of C8-C14 linear alkyl groups. The second component is 2-methyl-4-isothiazolin-3-one. In this case, the weight ratio of the nonionic surfactant to 2-methyl-4-isothiazolin-3-one is from 1:0.006 to 1:0.9143.