Synthetic Gingival Patch Graft Porous Polymeric Structure
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Solution Overview
Problem
Current solutions for gingival recession are invasive, time-consuming, and have limited long-term stability and efficiency, requiring multiple procedures and being tissue-based, which are bio-degradable.
Innovation Solution
A synthetic gingival patch graft with a porous polymeric structure, non-degradable, and biocompatible, fabricated using electrospinning techniques to create a tissue replacement patch with controlled pore sizes and thickness, potentially combined with active agents and a non-porous layer for enhanced stability and effectiveness.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If tissue-based grafting procedures are used to regenerate gum tissue, then new gum tissue can be formed to cover recession, but the graft material is bio-degradable and has limited long-term efficiency and stability
Solution Approach 1:
The patent changes the fundamental parameter of graft material composition from biological tissue to synthetic polymer. This parameter change transforms the material from bio-degradable to bio-stable, eliminating the degradation issue while maintaining the tissue regeneration function through the porous structure and surface properties of the synthetic material.
Solution Approach 2:
The patent employs composite material structure combining synthetic polymer matrix with porous architecture. This composite approach provides both the structural stability of synthetic materials and the functional properties (porosity, surface area) needed for tissue regeneration, resolving the contradiction between stability and biocompatibility.
2Reliability
If multiple dental operations are performed for gingival recession treatment, then comprehensive treatment can be achieved, but the procedure becomes time-consuming and complex
Solution Approach 1:
The patent merges multiple treatment functions into a single graft material that provides both immediate structural coverage and long-term regenerative support. The synthetic graft combines the functions of tissue replacement, structural support, and regenerative scaffolding that previously required multiple separate procedures and materials.
Solution Approach 2:
The synthetic graft material serves multiple functions simultaneously: it acts as an immediate barrier to protect underlying structures, provides structural support for tissue regeneration, and serves as a long-term stable framework. This multi-functionality eliminates the need for multiple specialized procedures.
3Area of stationary object
If thicker and longer grafts are used to cover larger recession areas, then more extensive coverage is achieved, but the graft thickness and length become limiting factors
Solution Approach 1:
The patent uses thin film architecture of synthetic polymer that can be flexed and adapted to various anatomical geometries. The thin film nature provides flexibility for surgical manipulation and adaptation to different recession patterns, while the porous structure maintains adequate porosity for tissue ingrowth despite reduced thickness.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The synthetic patch provides a stable, versatile, and lasting solution for gingival recession, simplifying the procedure and improving long-term tissue regeneration with enhanced osseointegration and bio-stability.
Implementation Method 1
a porous polymeric structure with pores of less than 5 μm
Implementation Method 2
fabricated using electrospinning techniques to create a tissue replacement patch
Data Source
Figure 1A~1E
Figure 2A
Figure 2B
AI summary
The invention provides a synthetic gingival patch graft having a porous polymeric structure and uses thereof in the method of treatment of periodontal diseases, conditions and symptoms.