Disposable Syringe Assembly Kit for Pre-filled Cartridges

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Solution Overview

Problem

The administration of medicinal products, particularly dental anaesthetics, faces challenges such as cumbersome and contaminated ampoule drawing, risk of injury from syringe racks, discomfort for patients, especially children, and high development and production costs for disposable pre-filled syringes, as well as the risk of cross-infection from multiple use.

Innovation Solution

A disposable pre-filled syringe assembly kit comprising a gripping means, needle mount, and plunger rod, made of plastic, which can be assembled with conventional cartridges to create a cost-efficient, hygienic, and compact injection device, with a protecting sleeve to prevent breakage and reduce cross-infection risk.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Object-affected harmful factors

If conventional syringe racks are used with pre-filled cartridges, then the injection device provides structural support and stability, but it creates a scary and threatening effect on patients, especially children, and increases the risk of cross-infection

Engineering Contradiction:
Improvepatient discomfort and cross-infection riskVSAvoidinjection device structure
Core Design Contradiction:
Object-affected harmful factorsVSDevice complexity

Solution Approach 1:

The invention divides the injection device into separate functional components: a disposable syringe unit containing the cartridge, needle, and plunger, and a reusable holder for positioning. This segmentation allows the syringe to be discarded after use, eliminating cross-infection risks, while the holder provides structural support without contacting the patient.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The syringe unit including the cartridge and needle is designed as a disposable component that is discarded after single use. This eliminates the need for cleaning and sterilization of the syringe itself, reducing cross-infection risks while maintaining structural functionality through the reusable holder.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

2Reliability

If disposable pre-filled syringes are designed and manufactured, then hygiene and safety are improved, but development and production costs are comparatively high

Engineering Contradiction:
Improvehygiene and safetyVSAvoiddevelopment and production cost
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The disposable syringe unit is designed to accommodate different cartridge types and medicinal products through universal compatibility features. The standardized interface allows the same syringe design to work with various cartridges, reducing the need for multiple specialized designs and lowering development and production costs.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The disposable syringe unit is discarded after single use to maintain hygiene, while the reusable holder is recovered and sterilized for continued use. This approach maintains high hygiene standards without requiring disposable holders, significantly reducing overall production costs.

Inventive Principle:
Principle #34Discarding and recovering

3Quantity of substance

If ampoule or vial drawing is performed, then medicinal product can be obtained, but the process is cumbersome and carries the risk of contamination with microorganisms or particulates

Engineering Contradiction:
Improvemedicinal product retrievalVSAvoidcontamination risk
Core Design Contradiction:
Quantity of substanceVSObject-affected harmful factors

Solution Approach 1:

The cartridge is pre-filled with the medicinal product under controlled conditions before leaving the manufacturing environment. This preliminary action eliminates the need for drawing operations at the point of use, preventing contamination with microorganisms or particulates while maintaining product availability.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The medicinal product is extracted from the sealed cartridge environment directly into the syringe chamber during the injection process, eliminating the need for separate drawing operations from ampoules or vials. This extraction occurs in a controlled manner that prevents contamination.

Inventive Principle:
Principle #2Taking out (Extraction)

4Ease of operation

If needle insertion into multiple dosage container is performed, then medicinal product can be administered, but medical staff is exposed to risk of injury

Engineering Contradiction:
Improvemedicinal product administrationVSAvoidmedical staff injury risk
Core Design Contradiction:
Ease of operationVSObject-affected harmful factors

Solution Approach 1:

The needle is integrated into the disposable syringe unit that is discarded after single use. This eliminates the need for needle reuse and associated injuries to medical staff, while maintaining the ability to administer medicinal products through the disposable needle.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Solution Approach 2:

The disposable syringe unit acts as an intermediary between the cartridge and the patient, containing the needle within a protected structure that is discarded after use. This intermediary design protects medical staff from needle injuries while enabling easy product administration.

Inventive Principle:
Principle #24Intermediary (Mediator)

Data Source

PatentEP2470243B1Assembly kit for preparing of a pre-filled syringe
Publication Date: 2019.10.02 SANOFI AVENTIS DEUT GMBH
  • EP2470243B1 patent drawingFigure 1~3
  • EP2470243B1 patent drawingFigure 4~7

AI summary

The present invention relates to an assembly kit for preparing of a pre-filled syringe and in particular to a method of preparing of such pre-filled syringe assemblies by means of an assembly kit, wherein the assembly kit comprises: - a gripping means (20, 21) to be attached to a proximal end section of a cartridge (10) which comprises an axially displaceable bung (12) for sealing of an interior volume of the cartridge (10) being pre-filled with an injectable medicinal product, - a needle mount (18, 19) to be attached to a distal end section of the cartridge (10) and providing a mount for a needle assembly to be coupled to the interior volume of the cartridge (10) in a fluid-transferring way, - a plunger rod (26; 30) connectable with the bung (12) of the cartridge (10) for applying distally directed thrust to the bung (12), wherein the cartridge (10) is at least partially embedded in a protecting sleeve.