Syringe System with Density-Matched Buoy for PRP Separation
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Solution Overview
Problem
Current methods for fractionating blood to prepare platelet-rich plasma (PRP) are inefficient in separating components based on specific gravity, leading to contamination and incomplete separation of desired layers.
Innovation Solution
A syringe system comprising a first syringe and a second syringe with buoys of specific gravities matching the boundaries between layers, allowing for precise separation of PRP through centrifugation, reducing contamination and improving layer separation efficiency.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Manufacturing precision
If conventional fractionation methods are used to separate blood components, then the separation process is simple, but the separation precision is poor leading to contamination between layers
Solution Approach 1:
A buoy is introduced as an intermediary object between the blood layers during centrifugation. The buoy's specific gravity is designed to match the interface between layers, allowing it to position itself precisely at the boundary and prevent mixing, thereby improving separation precision without fundamentally changing the centrifugation process
Solution Approach 2:
The specific gravity of the buoy is carefully selected to match the density boundary between blood components. By changing the physical parameter (specific gravity) of the added object to match the interface density, the system achieves precise layer separation and reduced contamination
2Productivity
If conventional fractionation methods are used, then the device structure is simple, but the separation efficiency is low leading to incomplete separation
Solution Approach 1:
The buoy acts as a mediator that facilitates complete separation by positioning at the layer interface. Its presence ensures that centrifugation proceeds efficiently with clear demarcation between layers, improving productivity despite the added structural element
Solution Approach 2:
The buoy is nested within the syringe barrel, fitting inside the existing centrifugation system. This nested configuration allows the buoy to perform its separation function without requiring external equipment or complex external structures
3Reliability
If conventional fractionation without buoys is used, then the operation is simple, but contamination between layers occurs
Solution Approach 1:
The buoy serves as a reliable intermediary that consistently positions at the layer interface during centrifugation. This reliable positioning prevents contamination and ensures consistent separation results, with the buoy requiring no complex operational steps from the user
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The syringe system effectively separates PRP from blood by using buoys with specific gravities that match the boundaries between layers, minimizing contamination and enhancing the purity and yield of PRP.
Implementation Method 1
A syringe system according to an aspect of the present disclosure includes a first syringe having a first syringe barrel; a second syringe having a second syringe barrel coupled to the first syringe in a movable manner from inside the first syringe barrel; and at least one of a first buoy located inside the first syringe barrel or a second buoy located inside the second syringe barrel
Implementation Method 2
A buoy type suspension fractionation system for fractionating blood or the like using a specific gravity difference is known
Data Source
AI summary
A syringe system includes a first syringe, a second syringe, and at least any one of a first buoy located inside a first syringe barrel or a second buoy located inside a second syringe barrel. The first syringe includes the first syringe barrel. The second syringe includes the second syringe barrel coupled to the first syringe in such a manner that at least part of the second syringe barrel is movable from inside the first syringe barrel.