Syringe Markings for Reconstituted Drug Concentrations

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Solution Overview

Problem

Traditional syringes used for reconstituted drugs and medicines in dry form lack clear indication of drug units, leading to confusion and potential errors due to varying concentration levels and different unit standards among manufacturers.

Innovation Solution

Syringes are designed with markings indicating specific reconstitution concentrations, allowing practitioners to select and use syringes marked according to the desired concentration, ensuring accurate measurement and administration of drug units, using visual indicia such as numbers, rings, or color codes to differentiate concentrations.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If traditional syringes are used for reconstituted drugs without concentration markings, then the syringe structure remains simple and manufacturing cost is low, but measurement precision and reliability are reduced due to confusion from varying concentration levels

Engineering Contradiction:
Improvedrug unit measurement accuracyVSAvoidsyringe marking system complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The syringe is pre-marked with concentration-specific unit measurements before use, allowing practitioners to directly measure accurate drug units without performing calculations during administration. The markings are prepared in advance for specific reconstitution concentrations (e.g., 100 units/mL, 50 units/mL), enabling immediate accurate measurement when the drug is reconstituted at the corresponding concentration.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

Different syringes are designed with different marking configurations tailored to specific reconstitution concentrations. Each syringe type has localized markings optimized for its intended concentration (e.g., syringes for 100 units/mL have different unit markings than syringes for 50 units/mL), allowing each syringe to provide locally optimized measurement precision for its specific application.

Inventive Principle:
Principle #3Local quality

2Adaptability or versatility

If syringes are marked with multiple concentration levels, then adaptability to different drug concentrations is improved, but device complexity and ease of operation deteriorate due to potential confusion among practitioners

Engineering Contradiction:
Improvecompatibility with different reconstitution concentrationsVSAvoidsyringe selection and use simplicity
Core Design Contradiction:
Adaptability or versatilityVSEase of operation

Solution Approach 1:

The syringe system is segmented into multiple distinct types, each designed and marked for a specific reconstitution concentration (e.g., separate syringes for 100 units/mL, 50 units/mL, 25 units/mL). This segmentation prevents confusion by ensuring each syringe type is clearly associated with one concentration level, making selection straightforward when the reconstitution concentration is known.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Visual indicators such as color-coded markings, colored rings, or color-coded syringe components are used to differentiate syringes designed for different reconstitution concentrations. These visual cues enable rapid identification and correct selection of the appropriate syringe type, improving ease of operation while maintaining adaptability across multiple concentration levels.

Inventive Principle:
Principle #32Color changes

Data Source

PatentUS10583254B1Syringe and method for reconstitution of dry-form drugs and medicines
Publication Date: 2020.03.10 TUCKER PETER L
  • US10583254B1 patent drawing
  • US10583254B1 patent drawing
  • US10583254B1 patent drawing

AI summary

A method of reconstituting and administering an injectable fluid distributed to practitioners in dry-form includes receiving a drug or medicine in dry form, selecting a reconstitution concentration for the drug or medicine, reconstituting a desired number of units of the drug or medicine by adding diluent to the dry-form drug or medicine, selecting a syringe having units marked according to the selected reconstitution concentration, drawing up a desired number of drug or medicine units using the selected syringe, and administering a desired number of units according to the unit markings on the selected syringe. Such a syringe includes a barrel, a plunger assembly that has a plunger handle and a piston, a needle, and a needle cap. The syringe includes a visual indicia, representing a first drug concentration contained in the barrel, that is distinguishable from a corresponding visual indicia, on a second syringe, representing a second drug concentration.