Syringe Mixing Chamber in Removable Cap

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Solution Overview

Problem

Conventional medical devices for mixing and administering biomedical agents face challenges such as contamination, incomplete extraction, and inaccurate dosing due to the need for multiple transfers and lack of efficient mixing capabilities, particularly for reconstituting lyophilized materials and preparing hemostatic agents.

Innovation Solution

A syringe-based mixing device with a removable cap containing an expandable chamber for thorough mixing of two components, allowing back-and-forth plunger movement to ensure complete intermixing, which can then be expressed onto a target, reducing the need for multiple containers and transfers.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If multiple separate vials and transfer devices are used for mixing components, then the components can be stored separately and mixed on demand, but the process becomes tedious and time-consuming with multiple transfers increasing contamination risk

Engineering Contradiction:
ImprovesterilityVSAvoidnumber of containers
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent combines multiple storage compartments and mixing functions into a single integrated device. The syringe contains multiple compartments for storing different components separately, while the mixing chamber allows thorough mixing of these components. This eliminates the need for multiple separate vials and transfer devices, reducing contamination risk while maintaining separate storage and on-demand mixing capabilities.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The syringe is divided into multiple compartments within a single body, allowing separate storage of different components. The mixing chamber is distinct from the storage compartments, creating a segmented structure that enables both separate storage and thorough mixing functions within one device, reducing the number of external containers needed.

Inventive Principle:
Principle #1Segmentation

2Adaptability or versatility

If components are transferred between multiple containers, then segregated storage is achieved, but incomplete extraction and inaccurate measuring occur

Engineering Contradiction:
Improvesegregated storageVSAvoiddosing accuracy
Core Design Contradiction:
Adaptability or versatilityVSMeasurement precision

Solution Approach 1:

The device merges storage and dosing functions into a single integrated system. Components are stored in separate compartments within the same syringe body, and the plunger mechanism allows precise control of component transfer and mixing. This eliminates the need for external transfer devices that cause incomplete extraction and measuring errors.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The mixing chamber acts as an intermediary between the storage compartments and the final delivery system. Components are transferred from storage compartments to the mixing chamber where thorough mixing occurs, ensuring complete extraction and accurate dosing before final administration, eliminating the need for additional transfer steps.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Stability of the object's composition

If vigorous mixing is performed to ensure thorough intermixing, then complete mixing is achieved, but the mixing time and number of transfers increase

Engineering Contradiction:
Improvemixing thoroughnessVSAvoidpreparation time
Core Design Contradiction:
Stability of the object's compositionVSLoss of time

Solution Approach 1:

The device combines storage compartments and mixing chamber into a single integrated system, allowing vigorous back-and-forth mixing to be performed within the same device without requiring transfer to external mixing containers. This achieves thorough mixing while reducing preparation time by eliminating additional transfer steps.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The mixing chamber is designed to accommodate dynamic back-and-forth movement of the plunger, enabling vigorous mixing action. The chamber geometry and flexible components allow efficient mixing through repeated displacement, achieving complete intermixing in fewer cycles compared to static mixing methods, thus reducing preparation time.

Inventive Principle:
Principle #15Dynamics

Data Source

PatentUS10596069B2Syringes with mixing chamber in a removable cap
Publication Date: 2020.03.24 ETHICON INC
  • US10596069B2 patent drawing
  • US10596069B2 patent drawing
  • US10596069B2 patent drawing

AI summary

The present invention is directed to a multi-compartment medical device for segregated storage and on demand mixing of at least two components and expression of the resulting mixture from the device. The mixing device comprises a syringe having an open end and outlet and containing a first component; and a cap with a fixed outer body and an expandable chamber contained therein, wherein said cap is removably attached to the outlet of the syringe and a cross-section of the cap is larger than a syringe cross-section and the cap is shorter than the syringe.