Pre-filled Syringe Opening System with Segmented Needle Carrier

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Solution Overview

Problem

Existing pre-filled syringes face issues with medicament compatibility with needle materials, contamination risks, and high production costs due to plastic usage, which affect efficacy and safety, and current solutions are not easily obtainable or reliable.

Innovation Solution

An opening system for pre-filled syringes with a coupling element and movable connecting means that keeps the needle separate until use, allowing aseptic operation and reducing plastic use, featuring intuitive and cost-effective assembly.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If the needle is kept in contact with the medicament in pre-filled syringes for long periods, then the syringe is ready for immediate use, but the medicament loses effectiveness or becomes harmful due to incompatibility with needle material

Engineering Contradiction:
Improvereadiness for useVSAvoidmedicament contamination
Core Design Contradiction:
Ease of operationVSObject-affected harmful factors

Solution Approach 1:

The system divides the needle and syringe into separate components that remain independent until the moment of use. The needle is housed in a protective carrier that prevents contact with the medicament, allowing the syringe to be stored and transported separately from the needle assembly.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent introduces a membrane as an intermediary barrier between the needle and medicament. This membrane remains intact during storage and transport, preventing direct contact between the needle and medicament, and is only breached when the device is activated for use.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Device complexity

If the needle is kept in contact with the medicament, then the syringe structure is simplified, but residues from the medicament formulation obstruct the needle preventing liquid flow

Engineering Contradiction:
Improvesyringe structureVSAvoidneedle obstruction
Core Design Contradiction:
Device complexityVSObject-generated harmful factors

Solution Approach 1:

The system separates the needle assembly from the syringe body, with each component optimized for its specific function. The needle remains isolated in its carrier until activation, preventing residue buildup and obstruction while maintaining a relatively simple overall structure.

Inventive Principle:
Principle #1Segmentation

3Reliability

If a cap or wrap is used to cover the syringe stem for sterilization and protection, then the syringe remains sterile until use, but production costs increase due to extra plastic usage

Engineering Contradiction:
Improvesterility maintenanceVSAvoidplastic consumption
Core Design Contradiction:
ReliabilityVSLoss of substance

Solution Approach 1:

The patent removes the need for separate protective caps or wraps by integrating the protection function directly into the needle carrier assembly. The carrier itself serves as the protective element, eliminating redundant plastic components while maintaining sterility.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The protective function and the needle housing function are merged into a single integrated carrier component. This consolidation eliminates the need for separate protective caps or wraps, reducing plastic consumption while maintaining sterility and protection.

Inventive Principle:
Principle #5Merging (Combining)

4Ease of operation

If an accessory with threaded ring and perforating needle is used to open the vial, then the medicament can be accessed, but the accessory is not easily obtainable and not completely reliable

Engineering Contradiction:
Improveopening capabilityVSAvoidoperation safety
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The opening mechanism is integrated into the needle carrier assembly itself, combining the perforating function with the needle delivery system. This integration ensures reliable operation while maintaining ease of use, eliminating the need for separate opening accessories.

Inventive Principle:
Principle #5Merging (Combining)

Data Source

PatentEP3419698B1Opening and supplying system for pre-filled containers, respective filled containers, and methods for their realization
Publication Date: 2026.03.18 BREVETTI ANGELA SRL
  • EP3419698B1 patent drawingFigure 1~6
  • EP3419698B1 patent drawingFigure 7~10
  • EP3419698B1 patent drawingFigure 11~13

AI summary

The present invention relates to an opening and liquid supplying system (100) for pre-filled containers (10, 30) equipped with a supplying end, comprising a coupling element (20), connecting means (6) movable from a first position to a second position, and movable protection means (9); the coupling element (20) has an end (27) closed and suitable for being punched, and first guiding means (21) for guiding the movement of the connecting means (6) movable from the first position, close to the closed end (27), to the second position, apart from such end, and vice versa; the connecting means (6) have engaging means (7) for engaging with the protection means (9) so as to move integrally along a second degree of freedom, different than the first degree of freedom, and first matches (1 1) for the first guiding means (21). The invention relates also to a respective pre-filled container equipped with such system and the method for realize them.