Syringe Piston Seal Assembly for Uniform Injection and Fluid Isolation

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Solution Overview

Problem

Current injectors and assisted injection systems fail to provide uniform, consistent, and controlled injections, and may allow leakage of driving fluid past the piston head, contaminating the medication.

Innovation Solution

An injection device with a piston seal system that includes a piston seal member, a coupling member, and a pressure delivery device, which prevents contamination by trapping any leaked fluid and ensuring uniform delivery of medication.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If a plunger rod is used to actuate the piston head, then the injection system can deliver medication to the patient, but the injection may not be uniform, consistent, or controlled

Engineering Contradiction:
Improveinjection controlVSAvoidinjection uniformity
Core Design Contradiction:
Ease of operationVSManufacturing precision

Solution Approach 1:

A pressurized gas or liquid medium is introduced as an intermediary between the actuator and the piston head. This intermediary transmits force uniformly across the piston head surface, replacing the non-uniform point contact of a plunger rod, thereby achieving controlled and consistent medication delivery

Inventive Principle:
Principle #24Intermediary (Mediator)

2Productivity

If a piston head system is used to deliver medication, then medication can be administered, but driving fluid may leak past the piston head and contaminate the medication

Engineering Contradiction:
Improvemedication deliveryVSAvoidmedication contamination
Core Design Contradiction:
ProductivityVSObject-affected harmful factors

Solution Approach 1:

The piston head is extracted or separated from direct contact with the medication chamber. The piston head operates in a dedicated actuation chamber filled with pressurized driving fluid, physically isolating the driving fluid from the medication and preventing contamination while maintaining delivery functionality

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The injection system is segmented into distinct chambers: a medication chamber containing the medication, and a separate actuation chamber containing the piston head and driving fluid. This segmentation prevents mixing between driving fluid and medication, eliminating contamination risk

Inventive Principle:
Principle #1Segmentation

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system provides uniform, consistent, and controlled medication delivery while preventing contamination by isolating pressurized media from the medication, ensuring accurate dosing and maintaining medication sterility.

Implementation Method 1

a pressure delivery device configured to convey pressurized media, from exterior of the container, into the container and into contact with the piston seal member to urge initial movement of the piston seal member and the piston head member

Methodology Applied
Scientific EffectPressurized media: Pressure Increase

Data Source

PatentEP3258995B1Syringe systems, piston seal systems, stopper systems, and methods of use and assembly
Publication Date: 2025.10.01 REGENERON PHARMACEUTICALS INC
  • EP3258995B1 patent drawingFigure 1
  • EP3258995B1 patent drawingFigure 2~3
  • EP3258995B1 patent drawingFigure 4~5

AI summary

A syringe system, piston seal systems, stopper systems, and methods for assembling and using the syringe systems. The piston seal system including a piston seal member and a piston head member. The injection system including a container, a piston seal system positioned within the container, and a stopper system coupled to an end of the container. The method of assembling an injection system, the method includes obtaining a container, a piston seal system, and a stopper system. The method also includes inserting the piston seal system into a cavity within the container. The method further includes securing the stopper system at an end of the container in an opening of the cavity. Methods of using the syringe system, piston seal systems, and stopper systems are also disclosed.