Syringe Stirring Paddle for Cell Therapy Hygiene

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Solution Overview

Problem

There is a lack of syringe apparatuses specifically designed for stirring and delivering mixtures containing cells in cell therapy, and existing syringes do not maintain hygiene during the therapeutic process effectively.

Innovation Solution

A syringe apparatus with a syringe barrel, a plunger, a stirring paddle, and a connecting member, where the plunger is movable and the stirring paddle is detachably disposed within the plunger, allowing for the stirring and delivery of single or multi-component compositions while maintaining hygiene through a needle and piston system with a dosage-control and needle-length control device.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If a conventional syringe is used for cell therapy, then the structure is simple and easy to manufacture, but it cannot effectively stir and deliver cell compositions while maintaining hygiene

Engineering Contradiction:

Improvehygiene maintenanceVSAvoidsyringe structure

Core Design Contradiction:

ReliabilityVSDevice complexity

Solution Approach 1:

The syringe is divided into multiple detachable components including a syringe barrel, plunger, stirring paddle, and connecting member. This segmentation allows each component to be separately sterilized and replaced, maintaining hygiene while enabling the complex functions of stirring and controlled delivery.

Inventive Principle:

Principle #1Segmentation

Solution Approach 2:

The plunger is designed to serve multiple functions: it can move axially to deliver the composition, rotate to drive the stirring paddle for mixing, and control the dosage through precise movement. This multi-functionality integrates stirring, delivery, and dosage control into a single device.

Inventive Principle:

Principle #6Universality (Multi-functionality)

2Stability of the object's composition

If a stirring mechanism is added to the syringe, then the composition can be stirred effectively, but the device complexity increases

Engineering Contradiction:

Improvecomposition mixingVSAvoidsyringe structure

Core Design Contradiction:

Stability of the object's compositionVSDevice complexity

Solution Approach 1:

The stirring paddle is merged with the plunger through the connecting member, allowing the plunger's rotational movement to directly drive the stirring action. This integration eliminates the need for a separate stirring mechanism while achieving effective composition mixing.

Inventive Principle:

Principle #5Merging (Combining)

Solution Approach 2:

The stirring paddle is designed to be rotatable relative to the plunger body, enabling dynamic stirring action during the delivery process. This dynamic capability ensures thorough mixing of cell compositions without requiring a complex fixed stirring mechanism.

Inventive Principle:

Principle #15Dynamics

3Reliability

If the plunger is made detachable and movable, then the hygiene can be maintained and dosage controlled, but the ease of operation decreases

Engineering Contradiction:

Improvehygiene maintenanceVSAvoidsyringe assembly

Core Design Contradiction:

ReliabilityVSEase of operation

Solution Approach 1:

The plunger and stirring paddle are pre-assembled as a integrated unit with the connecting member. This preliminary assembly simplifies the operation by reducing the number of separate components that need to be handled during use, while still maintaining the detachable feature for hygiene purposes.

Inventive Principle:

Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The apparatus effectively stirs and delivers cell compositions without damaging them, ensuring precision and safety during therapeutic processes by maintaining hygiene and allowing for controlled dosages and needle lengths, reducing human error.

Implementation Method 1

a plunger detachably disposed within the syringe barrel and being movable within the syringe barrel along the axial direction of the syringe barrel

Methodology Applied

Scientific EffectPressure application: Pressure Increase

Implementation Method 2

a stirring paddle detachably disposed within the plunger body with the plunger being movable relative to the stirring paddle along the axial direction

Methodology Applied

Scientific EffectMechanical stirring: Stirring

Data Source

PatentUS11376366B2Syringe apparatus for stirring and delivering composition containing cells

Publication Date: 2022.07.05 PLASTICS INDUSTRY DEVELOPMENT CENTER

AI summary

A syringe apparatus is provided for stirring and delivering single or multi-component compositions. The syringe apparatus comprises a syringe barrel, a plunger, a stirring paddle, and a connecting member. The plunger partially disposed within the syringe barrel is movable along an axial direction of the syringe barrel. The stirring paddle disposed within the syringe barrel has one end passing through the plunger and slidably disposed within the plunger. The syringe apparatus of the disclosure can stir the components and deliver the mixture safely for maintaining a good hygiene condition during the therapeutic process.