Systems and methods for shipping cryogenically-frozen materials

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Solution Overview

Problem

Traditional cryogenic dewars and shipping containers lack features to protect the lid from cracking, securely stack during transport, prevent coolant escape, and ensure safe transit of frozen materials, while also lacking data logging capabilities and appropriate documentation.

Innovation Solution

A cryogenic dewar with a lid that can house a data logging system and features for controlled coolant escape, combined with a shipping case that allows secure stacking, uses shock-absorbing linings, and includes load-bearing handles and a reliable closing mechanism.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Strength

If traditional cryogenic dewars use simple lid structures, then manufacturing is easier and cost is lower, but the lid cracks during transit when load is applied or dewar falls

Engineering Contradiction:
Improvelid strengthVSAvoidlid structure complexity
Core Design Contradiction:
StrengthVSDevice complexity

Solution Approach 1:

The lid is constructed using composite materials including a rigid outer shell and an energy-absorbing core layer. This composite structure provides both the strength needed to resist cracking under load or impact and a controlled complexity that manages the trade-off between durability and manufacturing simplicity.

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The lid incorporates an energy-absorbing core layer positioned between the outer shell and internal components. This cushioning element is pre-installed to absorb impact energies before they can crack the lid structure, preventing failure during transit without requiring complex active protection systems.

Inventive Principle:
Principle #11Beforehand cushioning (Prior cushioning)

2Reliability

If traditional shipping containers use heavy foam inserts for protection, then the dewar is well protected from vibrations and impacts, but shipping costs increase due to increased weight and volume

Engineering Contradiction:
Improveprotection reliabilityVSAvoidshipping container weight
Core Design Contradiction:
ReliabilityVSWeight of moving object

Solution Approach 1:

Instead of uniformly distributing heavy foam insulation throughout the shipping container, the design applies localized shock-absorbing elements only where impacts and vibrations are most likely to occur during transit. This targeted approach maintains protection reliability while minimizing unnecessary weight and volume.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The shipping container uses advanced shock-absorbing materials with superior energy absorption characteristics per unit weight compared to traditional foam. By changing the material parameters (density, elasticity, energy absorption capacity), the design achieves equivalent or better protection with reduced overall weight and volume.

Inventive Principle:
Principle #35Parameter changes

3Reliability

If traditional shipping containers use flimsy clamps for closing, then the container is easier to open and close, but the dewar can spill out during transit

Engineering Contradiction:
Improveclosing mechanism reliabilityVSAvoidclosing mechanism operation
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The closing mechanism incorporates curved or rounded structural elements that distribute locking forces more evenly across the container opening. This geometric design provides robust security against accidental opening during transit while maintaining smooth operation surfaces that do not complicate the closing action.

Inventive Principle:
Principle #14Spheroidality (Curvature)

Solution Approach 2:

The closing mechanism is designed with self-latching features that automatically engage when the container is closed, providing secure locking without requiring complex manual operations. The mechanism serves itself by using the closing motion to trigger the latching action, ensuring reliability while maintaining ease of use.

Inventive Principle:
Principle #25Self-service

4Loss of information

If traditional dewars lack data logging capabilities, then the device is simpler and cheaper, but there is no way to track and verify environmental conditions during transit

Engineering Contradiction:
Improveenvironmental condition dataVSAvoiddewar system complexity
Core Design Contradiction:
Loss of informationVSDevice complexity

Solution Approach 1:

The dewar lid is designed as a multi-functional component that simultaneously serves as a structural protective element and as a housing for the data logging system. By integrating the sensor and data storage functions into the existing lid structure, the design captures environmental condition information without adding separate complex subsystems.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The design replaces manual environmental monitoring with electronic sensors and digital data logging capabilities integrated into the dewar. This substitution of mechanical/manual processes with electronic systems enables automatic tracking and verification of temperature and other conditions throughout transit.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

5Reliability

If traditional dewars lack coolant escape prevention features, then the dewar structure is simpler, but unregulated coolant escape occurs during transport

Engineering Contradiction:
Improvecoolant containment reliabilityVSAvoidcoolant control system complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The dewar incorporates self-regulating pressure relief features that automatically control coolant vapor escape without requiring external intervention or complex control systems. The design uses the inherent physical properties of the coolant and container to self-regulate pressure and prevent uncontrolled escape during transport.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The coolant containment system utilizes controlled phase change parameters to manage vapor pressure and escape rates. By designing the containment structure to accommodate and regulate the phase transition characteristics of the coolant, the system maintains reliable containment while allowing controlled vapor release to prevent pressure buildup.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Ensures safe and efficient transport of frozen materials by protecting the dewar lid, preventing coolant escape, enabling secure stacking, and providing data logging and documentation capabilities.

Implementation Method 1

a shock-absorbing lining disposed on an inner surface of the one or more walls and configured to accept a cryogenic shipping container

Methodology Applied
Scientific EffectShock absorption: Damping

Implementation Method 2

a lid configured to reversibly engage with the insulated housing such that the lid forms a seal over the insulated housing when the lid is engaged with the insulated housing

Methodology Applied
Scientific EffectSealing: Physical Containment

Implementation Method 3

an insulated housing including: a cavity for containing the frozen material

Methodology Applied
Scientific EffectThermal insulation: Thermal Insulation

Data Source

PatentUS12522426B2Systems and methods for shipping cryogenically-frozen materials
Publication Date: 2026.01.13 KITE PHARMA INC
  • US12522426B2 patent drawing
  • US12522426B2 patent drawing
  • US12522426B2 patent drawing

AI summary

Embodiments of the disclosure relate to shipping cases, dewars, and systems for transporting a frozen material. More specifically, the embodiments described herein include and/or enable dewar lid protective systems, data logging enablement, controlled coolant escape, efficient stacking options during transport, spill protection to ensure safe and effective transport of frozen samples and materials among other things. An exemplary use for the systems described herein includes reliable shipping for frozen materials at specified environmental conditions which can be tracked and verified.