Tamarind Seed Polysaccharide Anti-inflammatory Compositions

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Solution Overview

Problem

Current treatments for inflammatory diseases, such as dermatitis and mucositis, often come with significant side effects and limited effectiveness, particularly for conditions like psoriasis and chemotherapy-induced mucositis, where there is a need for a more convenient and effective anti-inflammatory solution.

Innovation Solution

The use of tamarind seed polysaccharide (TSP) as an active ingredient in anti-inflammatory pharmaceutical and dermocosmetic compositions for topical administration, either alone or in combination with other active ingredients like antimicrobial, anti-inflammatory, and wound-healing agents, to provide a synergistic effect on reducing inflammation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional anti-inflammatory treatments are used, then inflammation is reduced, but significant side effects occur

Engineering Contradiction:
Improveanti-inflammatory effectivenessVSAvoidside effects
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent employs a naturally derived, biodegradable polysaccharide from tamarind seeds as a temporary, safe anti-inflammatory agent that does not accumulate harmful effects in the body, replacing conventional drugs with significant side effects

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Solution Approach 2:

The invention combines tamarind seed polysaccharide with other active ingredients like antimicrobial, anti-inflammatory, and wound-healing agents to create a composite formulation that provides synergistic effects while minimizing individual component dosages and associated side effects

Inventive Principle:
Principle #40Composite materials

2Reliability

If current anti-inflammatory treatments are used, then some inflammatory conditions are treated, but effectiveness is limited for severe conditions like psoriasis and chemotherapy-induced mucositis

Engineering Contradiction:
Improveanti-inflammatory effectivenessVSAvoidapplicability to different inflammatory conditions
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent formulates a versatile anti-inflammatory composition based on tamarind seed polysaccharide that can be applied to multiple types of inflammatory conditions including dermatitis, psoriasis, and mucositis, providing a universal treatment approach for various inflammatory diseases

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The composition integrates multiple active ingredients with different mechanisms of action (antimicrobial, anti-inflammatory, wound-healing) to address the complex pathophysiology of severe inflammatory conditions that resist single-agent therapy

Inventive Principle:
Principle #40Composite materials

Data Source

PatentUS10130652B2Anti-inflammatory compositions
Publication Date: 2018.11.20 INDENA SPA

AI summary

The present invention relates to the use as an anti-inflammatory of tamarind seed polysaccharide (TSP) and to anti-inflammatory compositions which contain it as active ingredient. Anti-inflammatory compositions containing TSP are particularly useful for topical administration in the treatment of inflammatory diseases of the skin and mucosa.