Tapered Insert Sample Recovery Device
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Solution Overview
Problem
Current devices and methods for sample collection and transportation often result in insufficient material for diagnostic testing due to limited swab surface area and inefficient sample isolation, leading to the need for multiple sample submissions and reduced subject compliance.
Innovation Solution
A sample recovery and collection device featuring a tube with a tapered insert that applies pressure to a swab tip, effectively transferring biological samples into a solution for enhanced yield and minimizing bacterial contamination.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If a single swab is used for sample collection, then the collection process is simple and non-invasive, but the sample yield is insufficient for diagnostic testing
Solution Approach 1:
The device divides the sample collection process into multiple independent swab insertions, allowing multiple swabs to be used sequentially with the same tube, thereby increasing total sample yield while maintaining simple operation
Solution Approach 2:
The insert structure is nested within the tube, creating a compact configuration that allows multiple swabs to be processed through the same device without requiring multiple separate containers or complex handling procedures
2Quantity of substance
If multiple swabs are used to increase sample material, then sufficient diagnostic material can be obtained, but the collection process becomes more complex and time-consuming
Solution Approach 1:
The tube and insert combination serves multiple functions: it contains the solution, provides a standardized insertion path for multiple swabs, and facilitates efficient sample transfer, thereby simplifying the overall process while accommodating multiple swabs
Solution Approach 2:
The tube is pre-filled with solution before sample collection, and the insert is pre-positioned within the tube, so that when swabs are inserted, the sample transfer process occurs automatically without requiring additional manual steps
3Device complexity
If traditional transport methods are used, then the device is simple, but sample integrity is compromised during transportation
Solution Approach 1:
The insert is nested within the tube, creating a compact, self-contained structure that protects the sample and solution from external contaminants and mechanical damage during transportation while maintaining a simple overall device design
Solution Approach 2:
The insert acts as an intermediary structure between the swab and the solution, facilitating controlled sample transfer and providing a physical barrier that helps maintain sample integrity during handling and transport
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The device achieves a significant increase in DNA, RNA, and protein yield, with up to 5.8-fold DNA yield improvement and minimal bacterial contamination, facilitating more efficient diagnostic testing and improved subject compliance.
Implementation Method 1
The tapered opening may be configured to receive a swab and apply pressure to a tip of the swab. The pressure exerted on the tip of the swab may cause a sample carried by the swab tip to be squeezed into the tube to mix with the solution.
Implementation Method 2
The cap may include an O-ring and may be removably secured to the tube for sealing the tube.
Data Source
AI summary
A sample recovery and collection device comprises a tube, a cap, an insert, and an opening. The cap includes an O-ring and is removably secured to the tube for sealing the tube. The insert includes a first end having a ring that is adhered to the tube and second end opposite the first end. The insert also includes a first leg, a second leg, and a third leg, each coupled to and extending from the ring to the second end. The opening extends from the ring to the second end and the insert defines a diameter.