Optical Measurement System Using Target-Reference Tissue Spectra

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Solution Overview

Problem

Conventional methods for assessing mucosal tissue health, such as endoscopy and optical biopsy, suffer from limitations including poor image resolution, requirement of anesthesia, and reliance on subjective image interpretation, making accurate diagnosis challenging.

Innovation Solution

An optical measurement system that utilizes spectrum signals to calculate health parameters by comparing target and reference tissue areas, using a light source, fiber module, and optical detection device to obtain and analyze spectral signals, providing quantifiable health status indicators like tissue oxygenation, proliferation, and inflammation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If endoscopy is used to detect mucosal tissue health, then early diagnosis capability is improved, but image resolution remains poor and requires anesthesia or contrast agents

Engineering Contradiction:
Improveearly diagnosis capabilityVSAvoidimage resolution
Core Design Contradiction:
ReliabilityVSMeasurement precision

Solution Approach 1:

The patent replaces the mechanical imaging system of endoscopy with an optical spectroscopy system. Instead of using cameras and lenses to capture images, the system uses light sources and spectrometers to analyze the spectral characteristics of mucosal tissue, substituting mechanical imaging with optical field-based measurement.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent changes the measurement parameter from visual image information to spectral signal information. By measuring the absorption and reflection characteristics of light across different wavelengths, the system transforms the diagnostic basis from qualitative image interpretation to quantitative spectral analysis, improving both resolution and objectivity.

Inventive Principle:
Principle #35Parameter changes

2Ease of operation

If conventional optical biopsy is used for real-time imaging, then tissue specimen collection is avoided, but diagnostic accuracy suffers due to subjective image interpretation

Engineering Contradiction:
Improvereal-time imaging capabilityVSAvoiddiagnostic accuracy
Core Design Contradiction:
Ease of operationVSMeasurement precision

Solution Approach 1:

The patent replaces subjective visual interpretation with automated spectral analysis. The system uses computers to process spectral signals and objectively determine tissue health status, eliminating human subjectivity from the diagnostic process while maintaining real-time capability.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent introduces spectral signals as an intermediary between the tissue and the diagnostic conclusion. Instead of directly interpreting images, the system measures spectral characteristics that serve as objective intermediaries, providing a quantifiable basis for diagnosis that reduces subjective judgment.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Difficulty of detecting and measuring

If endoscopy with contrast agents is used for diagnosis, then detection capability is improved, but patient safety deteriorates due to side effects from contrast agents

Engineering Contradiction:
Improvedetection capabilityVSAvoidside effects from contrast agents
Core Design Contradiction:
Difficulty of detecting and measuringVSObject-affected harmful factors

Solution Approach 1:

The patent replaces contrast agent-based enhancement with intrinsic optical property measurement. By analyzing the natural absorption and reflection characteristics of tissue at different wavelengths, the system achieves detection capability without introducing external substances that could cause harmful side effects.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system offers real-time, accurate, and objective health assessments of mucosal tissues, reducing discomfort and human error, and providing precise diagnostic information without invasive procedures.

Implementation Method 1

a light source device configured to generate light to illuminate a target tissue area and a reference tissue area of a human body

Methodology Applied
Scientific EffectLight emission: Light

Implementation Method 2

a fiber module coupled to the light source device, and configured to direct and transmit the light generated by the light source device to illuminate the target tissue area and the reference tissue area of the human body, and receive response beams from the target tissue area and the reference tissue area of the human body

Methodology Applied
Scientific EffectOptical fiber transmission: Optical Fibre

Implementation Method 3

an optical detection device coupled to the fiber module, and configured to detect the response beams from the target tissue area to obtain a target spectrum signal of the target tissue area and detect the response beams from the reference tissue area to obtain a reference spectrum signal of the reference tissue area

Methodology Applied
Scientific EffectSpectrum detection: Absorption Spectroscopy

Data Source

PatentUS12414736B2Optical measurement system
Publication Date: 2025.09.16 ADVANCED ACEBIOTEK CO LTD
  • US12414736B2 patent drawing
  • US12414736B2 patent drawing
  • US12414736B2 patent drawing

AI summary

An optical measurement system is provided, which includes a light source device, a fiber module, an optical detection device and a processing circuit. The light source device is configured to generate light to illuminate a target tissue area and a reference tissue area of a human body. The fiber module is configured to direct and transmit the light to illuminate the target tissue area and the reference tissue area and receive response beams from the target tissue area and the reference tissue area. The optical detection device is configured to detect the response beams from the target tissue area to obtain the target spectrum signal and detect the response beams from the reference tissue area to obtain a reference spectrum signal. The processing circuit configured to calculate a health status parameter of the target tissue area according to the target spectrum signal and reference spectrum signal.