Target Substance Concentration Calculation Accuracy
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Solution Overview
Problem
Existing methods for detecting target substances in samples, such as in medical diagnosis and research, often underestimate the number of target substances due to the requirement that only individual separated compartments with a target capturing substance are considered for measurement.
Innovation Solution
A method that involves acquiring an image of multiple individual separated compartments, detecting the presence or absence of the target capturing substance in each compartment, and calculating the concentration of the target substance based on the number of compartments with and without the target capturing substance.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Device complexity
If only individual separated compartments with target capturing substance are considered for measurement, then the measurement process is simplified, but the concentration calculation accuracy deteriorates due to underestimation of target substances
Solution Approach 1:
The patent segments the measurement process into two distinct analysis groups: compartments with target capturing substance and compartments without target capturing substance. This segmentation allows comprehensive analysis of all compartments while maintaining organized, manageable processing streams for each group, resolving the contradiction between process simplicity and measurement accuracy.
Solution Approach 2:
The patent applies universal analysis methods to both types of compartments (with and without target capturing substance), enabling the same detection and calculation procedures to be applied across all compartments. This multi-functional approach ensures consistent, accurate measurement throughout the entire sample without requiring separate specialized processes.
2Measurement precision
If all individual separated compartments are analyzed for target substance, then measurement accuracy improves, but the calculation complexity increases
Solution Approach 1:
The patent divides the calculation process into separate streams for compartments with target capturing substance and compartments without target capturing substance. Each stream applies appropriate calculation methods tailored to its specific characteristics, reducing overall computational complexity while maintaining comprehensive accuracy across all compartments.
Solution Approach 2:
The patent applies different levels of analysis to different compartment groups based on their specific needs. Compartments with target capturing substance receive one type of analysis while compartments without receive another type, avoiding unnecessary computational steps in each group while ensuring sufficient accuracy where required.
Data Source
AI summary
The present disclosure provides a method for improving accuracy of calculating an amount of a target substance. A method for processing information includes acquiring an image including, a plurality of individual separated compartments, detecting presence of a target capturing substance in each of the individual separated compartments in the image, and calculating an amount of a target substance based on information regarding 1) the number of the individual separated compartments where the target capturing substance is detected and 2) the number of compartments in which the target substance is detected among the individual separated compartments in which the target capturing substance is detected and information regarding 3) the number of the individual separated compartments in which the target capturing substance is not detected and 4) the number of compartments in which the target substance is detected among the individual separated compartments in which the target capturing substance is not detected.