TBZC-TMG Complex for Zinc Ion Delivery in Oral Care
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Solution Overview
Problem
Current oral care compositions using soluble zinc salts face challenges such as unpleasant taste and mouthfeel, interference with foaming and cleaning, and inefficient delivery of zinc due to insolubility of tetrabasic zinc chloride (TBZC), which limits their effectiveness in preventing dental erosion and hypersensitivity.
Innovation Solution
The formation of a soluble complex between tetrabasic zinc chloride (TBZC) and N,N,N-trimethylglycine (TMG) in both its free and acidified forms, which provides effective zinc ion delivery to the teeth, reduces sensitivity by plugging dentinal tubules, and enhances shine, while avoiding the drawbacks of conventional zinc-based products.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Quantity of substance
If soluble zinc salts are used in oral care compositions, then zinc ions are delivered to the teeth, but unpleasant taste and mouthfeel occur
Solution Approach 1:
The patent uses soluble zinc salts as intermediaries to deliver zinc ions to the teeth. The zinc ions act as the active component that provides dental benefits while the soluble salt form ensures adequate delivery, resolving the contradiction between effective zinc delivery and acceptable sensory properties.
2Quantity of substance
If soluble zinc salts are used in oral care compositions, then zinc ions are delivered to the teeth, but foaming and cleaning are interfered with
Solution Approach 1:
The patent modifies the chemical parameters of zinc delivery by using soluble zinc salts with specific properties that allow zinc ion delivery while maintaining compatibility with surfactants. This parameter change resolves the interference issue with foaming and cleaning functions.
3Quantity of substance
If tetrabasic zinc chloride is used in oral care compositions, then zinc delivery is improved, but solubility is insufficient
Solution Approach 1:
The patent changes the solubility parameter of tetrabasic zinc chloride by using it in combination with other ingredients or in specific formulation conditions that enhance its dissolution and zinc ion release, thereby resolving the contradiction between improved zinc delivery and adequate solubility.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The TBZC-TMG complex effectively protects against dental erosion, reduces bacterial colonization and biofilm, and provides enhanced whitening and sensitivity relief without the taste and mouthfeel issues associated with traditional zinc-based products.
Implementation Method 1
the formation of a soluble complex between tetrabasic zinc chloride (TBZC) and N,N,N-trimethylglycine (TMG)
Implementation Method 2
provides effective zinc ion delivery to the teeth, reduces sensitivity by plugging dentinal tubules
Implementation Method 3
Zinc has been shown to have antibacterial properties in plaque and caries studies
Data Source
AI summary
The invention provides oral care compositions comprising a mixture of tetrabasic zinc halide and trimethylglycine, in free or orally acceptable salt form. Methods of making and using the compositions are also provided.