Tebuconazole Azoxystrobin Fludioxonil Pesticidal Combinations
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Solution Overview
Problem
Current combinations of pesticidal active ingredients for controlling pathogens and pests are inadequate in terms of biological properties, phytotoxicity, and environmental and worker exposure, particularly when pathogens become resistant, necessitating improved methods for pathogenic and pest control in agricultural practices.
Innovation Solution
A combination of tebuconazole, azoxystrobin, and fludioxonil, optionally with tefluthrin and thiamethoxam, is used to enhance pesticidal activity, providing synergistic effects that improve control and prevention of pathogenic and pest damage on plant propagation materials and plants, reducing exposure risks and increasing crop tolerance.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If known combinations of active ingredients (e.g., azoxystrobin, fludioxonil, difenoconazole) are used for seed treatments, then pathogenic control is achieved, but biological properties become insufficient when pathogens develop resistance
Solution Approach 1:
The patent combines three fungicides with different modes of action (tebuconazole - triazole, azoxystrobin - strobilurin, fludioxonil - phenylpyrrole) into a single composition. This merging of multiple chemical classes with distinct mechanisms of action ensures that when pathogens develop resistance to one component, the other components maintain efficacy, thereby resolving the contradiction between reliable pathogenic control and adaptability to resistance.
Solution Approach 2:
The invention creates a composite pesticidal formulation containing tebuconazole, azoxystrobin, and fludioxonil in specific ratios. This composite approach integrates multiple active ingredients with complementary properties, providing both immediate pathogenic control and long-term adaptability against evolving pathogen resistance through synergistic interactions among the components.
2Reliability
If higher doses of single active ingredients are applied to improve pathogenic control, then control effectiveness increases, but phytotoxicity and environmental exposure increase
Solution Approach 1:
By combining three fungicides at optimized low doses (tebuconazole 5-20 g/ha, azoxystrobin 10-40 g/ha, fludioxonil 5-20 g/ha), the formulation achieves superior pathogenic control while keeping individual ingredient exposures low. This merging approach reduces phytotoxicity risks and environmental burden compared to applying higher doses of single ingredients, as each component works synergistically at lower concentrations.
3Reliability
If existing fungicide combinations are used, then some pathogenic control is achieved, but crop tolerance and activity against phytopathogenic fungi do not satisfy agricultural needs
Solution Approach 1:
The tri-component formulation provides multi-functional activity covering a broad spectrum of phytopathogenic fungi including powdery mildews, rusts, leaf spots, and blights. The combination of tebuconazole (ergosterol biosynthesis inhibitor), azoxystrobin (respiratory electron transport inhibitor), and fludioxonil (cell wall synthesis disruptor) creates a universal solution that satisfies diverse agricultural needs while maintaining high crop tolerance through balanced dosing.
Data Source
AI summary
A method of controlling or preventing pathogenic damage or pest damage in a plant propagation material, a plant, parts of a plant and/or plant organs that grow at a later point in time, which comprises applying simultaneously on the plant, part of the plant, plant organs, plant propagation material or a surrounding thereof a combination comprising (I) tebuconazole, (II) azoxystrobin and (III) one or more of insecticides and/or fludioxonil, and optionally (IV) one or more customary formulation auxiliaries, provided that where tefluthrin and thiamethoxam are both present, then the combination comprises more than five active ingredients.