Temperature-Responsive Skin Adhesion for Stable Tissue Cooling

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Solution Overview

Problem

Conventional methods for maintaining stable thermal and physical contact between an applicator and tissue during cooling treatments, such as cryolipolysis, are limited by suction and restraints, which can cause discomfort, reduce effective contact area, and lead to false sensor readings due to patient movement.

Innovation Solution

Utilizing a temperature-dependent adhesive that strengthens adhesion between the applicator and skin by increasing viscosity and tackiness during cooling, eliminating the need for suction and restraints.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If suction and restraints are used to maintain contact between applicator and skin, then stable thermal contact is improved, but patient comfort deteriorates and device complexity increases

Engineering Contradiction:
Improvestable thermal contactVSAvoidpatient comfort
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The adhesive's viscosity and adhesion strength are changed as a function of temperature. At application temperature, the adhesive has low viscosity for easy application, then undergoes a viscosity transition at a predetermined temperature during cooling to increase adhesion strength, maintaining contact without suction or restraints

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The adhesive composition combines multiple components including a polymer component, plasticizer, and optional additives to achieve the desired temperature-dependent viscosity transition and adhesion characteristics that eliminate the need for mechanical restraints

Inventive Principle:
Principle #40Composite materials

2Reliability

If suction is used to maintain applicator position, then contact stability is improved, but device complexity and energy consumption increase

Engineering Contradiction:
Improvecontact stabilityVSAvoiddevice complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The adhesive undergoes a temperature-dependent viscosity transition from low viscosity at application temperature to high viscosity at predetermined temperature, providing self-adhesion that eliminates the need for suction mechanisms and complex device components

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The mechanical suction system is replaced with a temperature-responsive adhesive system that uses thermal energy to trigger viscosity change and adhesion, simplifying the device by eliminating motors, vacuum pumps, and associated control systems

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Reliability

If restraints are applied to prevent patient motion, then applicator stability is improved, but patient comfort and ease of operation worsen

Engineering Contradiction:
Improveapplicator stabilityVSAvoidpatient comfort
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The adhesive's adhesion strength is dynamically changed through temperature-dependent viscosity transition, providing strong bonding during treatment without requiring external restraints that would restrict patient movement and cause discomfort

Inventive Principle:
Principle #35Parameter changes

4Ease of manufacture

If conventional adhesives are used that maintain constant adhesion, then application is simple, but they cannot provide enhanced adhesion during cooling treatment

Engineering Contradiction:
Improveapplication simplicityVSAvoidadhesion during cooling
Core Design Contradiction:
Ease of manufactureVSReliability

Solution Approach 1:

The adhesive is formulated with temperature-responsive components that cause a viscosity transition at a predetermined temperature, transforming from a easily applied low-viscosity state to a high-adhesion state during the cooling treatment process

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The adhesive properties are made dynamic rather than static, changing viscosity and adhesion strength in response to temperature changes during treatment, allowing the same material to provide both easy application and strong bonding

Inventive Principle:
Principle #15Dynamics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Ensures stable thermal and physical contact, reduces relative movement between the applicator and skin, and prevents false sensor readings by enhancing adhesive strength by a factor of up to 30x, thereby improving treatment efficacy.

Implementation Method 1

The use of a temperature-dependent adhesive that strengthens adhesion between the skin and the applicator as it cools, eliminating the need for suction and restraints by maintaining stable contact through increased viscosity and tackiness

Methodology Applied
Scientific EffectTemperature-dependent viscosity change:

Implementation Method 2

U.S. Patent Publication No. 2008/0287839 entitled 'METHOD OF ENHANCED REMOVAL OF HEAT FROM SUBCUTANEOUS LIPID-RICH CELLS AND TREATMENT APPARATUS HAVING AN ACTUATOR'

Methodology Applied
Scientific EffectHeat transfer: Conduction (thermal)

Implementation Method 3

The present disclosure is related to cooling of tissue, such as in the context of cryolipolysis and cryolysis

Methodology Applied
Scientific EffectCooling: Cooling

Data Source

PatentEP3399950B1Temperature-dependent adhesion between applicator and skin during cooling of tissue
Publication Date: 2026.05.20 ZELTIQ AESTHETICS INC
  • EP3399950B1 patent drawingFigure 1~2
  • EP3399950B1 patent drawingFigure 3~4
  • EP3399950B1 patent drawingFigure 5~6

AI summary

A method and apparatus in accordance with a particular embodiment of the present invention includes applying adhesive onto skin of a human subject. An applicator is then brought into contact with the adhesive such the adhesive is disposed between the applicator and the subject's skin. The applicator is activated to cool a tissue region via the subject's skin, via the heat-transfer surface of the applicator, and via the adhesive. While the tissue region cools, the adhesive also cools, thereby reversibly strengthening adhesion between the subject's skin and the heat-transfer surface and forming a strong bond therebetween. The strengthened adhesion inhibits any movement of the applicator relative to the skin. After cooling the tissue region, the adhesive is warmed, thereby weakening the adhesion which allows the heat-transfer surface of the applicator to be easily separated from the skin.