Template-Based Anatomical Segmentation of Medical Images

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Solution Overview

Problem

Multi-atlas segmentation techniques for medical images face high computational costs and often result in less accurate atlas propagation when using a common template for all target images, leading to reduced segmentation accuracy and increased processing time.

Innovation Solution

A template library is employed to select optimal templates for each target image, reducing the number of online registrations required and utilizing offline registrations to achieve faster and more accurate anatomical segmentation by performing pairwise deformable registration with a subset of selected templates.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If multi-atlas segmentation is performed using standard techniques, then segmentation accuracy is improved, but computational cost and processing time increase significantly

Engineering Contradiction:
Improvesegmentation accuracyVSAvoidprocessing time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent pre-computes and stores similarity metrics between each template and all target images before actual segmentation. This preliminary action allows the system to quickly retrieve and select appropriate templates during segmentation without performing computationally intensive similarity calculations at runtime, thereby maintaining accuracy while reducing processing time

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent divides the large set of templates into multiple subsets or groups. Instead of comparing against all templates, the system selectively processes only relevant template subsets based on preliminary similarity metrics or anatomical characteristics, reducing the computational burden while preserving segmentation accuracy through targeted template selection

Inventive Principle:
Principle #1Segmentation

2Device complexity

If a common template is used for all target images, then device complexity is reduced, but segmentation accuracy deteriorates due to less accurate atlas propagation

Engineering Contradiction:
Improvesystem complexityVSAvoidsegmentation accuracy
Core Design Contradiction:
Device complexityVSMeasurement precision

Solution Approach 1:

The patent implements a dynamic template selection mechanism that adapts the template set based on each target image's characteristics. The system automatically identifies and selects the most appropriate templates for each specific target image rather than using a fixed common template, allowing the system complexity to increase only when and where it improves accuracy

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The patent applies different templates or template subsets to different regions or types of target images based on their specific anatomical characteristics. This local customization ensures that each target image receives the most appropriate template matching its unique features, improving segmentation accuracy without requiring all possible templates to be processed for every image

Inventive Principle:
Principle #3Local quality

3Measurement precision

If the number of templates is increased, then segmentation accuracy is improved, but computational cost increases

Engineering Contradiction:
Improvesegmentation accuracyVSAvoidcomputational cost
Core Design Contradiction:
Measurement precisionVSUse of energy by moving object

Solution Approach 1:

The patent performs partial template processing by selectively applying templates only to relevant regions or cases. The system identifies and processes only the necessary subset of templates for each target image rather than exhaustively processing all available templates, achieving sufficient segmentation accuracy with reduced computational effort

Inventive Principle:
Principle #16Partial or excessive action

Solution Approach 2:

The system pre-evaluates and ranks templates based on their relevance to target images before actual segmentation. This preliminary filtering creates a prioritized template list that guides subsequent processing, ensuring that computational resources are focused on the most promising templates while less relevant ones are skipped or processed minimally

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS11094069B2Template based anatomical segmentation of medical images
Publication Date: 2021.08.17 MERATIVE US LP
  • US11094069B2 patent drawing
  • US11094069B2 patent drawing
  • US11094069B2 patent drawing

AI summary

A mechanism is provided in a data processing system comprising a processor and a memory, the memory comprising instructions executed by the processor to specifically configure the processor to implement a multi-atlas segmentation engine. An offline registration component performs registration of a plurality of atlases with a set of image templates to thereby generate and store, in a first registration storage device, a plurality of offline registrations. The atlases are annotated training medical images and the image templates are non-annotated medical images. The multi-atlas segmentation engine receives a target image. An image selection component selects a subset of image templates in the set of image templates based on the target image. An online registration component performs registration of the subset of image templates with the target image to generate a plurality of online registrations. The multi-atlas segmentation engine retrieves offline registrations corresponding to the subset of image templates from the first registration storage device. The multi-atlas segmentation engine performs segmentation of the target image based on the retrieved offline registrations corresponding to the subset of image templates and the plurality of online registrations. The segmentation applies labels to anatomical structures present in the target image based on the retrieved offline registrations and the plurality of online registrations to thereby output a modified target image.