Terahertz Endoscopy Array for Deeper Tissue Imaging

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current terahertz imaging systems for medical diagnostics face limitations in detectable penetration depth and image acquisition time due to low radiation power of sources and detection sensitivity, as well as mechanical scanning processes.

Innovation Solution

The development of a terahertz imaging system utilizing a two-dimensional array of large area plasmonic photoconductive terahertz sources and detectors, compatible with commercially available endoscopes, which enhances output power, detection sensitivity, and signal-to-noise ratio, allowing for deeper penetration and faster image acquisition through phase-modulated dual-laser-synchronized control and cross-registration algorithms for panoramic imaging.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Power

If conventional terahertz sources and detectors are used, then the system structure is simple, but the radiation power is low and detection sensitivity is poor

Engineering Contradiction:
Improveradiation powerVSAvoidsystem structure
Core Design Contradiction:
PowerVSDevice complexity

Solution Approach 1:

The patent combines multiple terahertz sources and detectors into a unified array system, merging their individual outputs to achieve higher radiation power and detection sensitivity while maintaining coordinated operation through synchronized control

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent transitions from single-point terahertz sources and detectors to two-dimensional arrays, adding spatial dimensionality to multiply the effective radiation power and detection capability across multiple elements simultaneously

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Productivity

If mechanical scanning processes are used, then the system structure is simple, but the image acquisition time is long

Engineering Contradiction:
Improveimage acquisition rateVSAvoidsystem structure
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent replaces mechanical scanning systems with electronic array-based parallel detection, substituting moving mechanical parts with stationary multi-element arrays that can simultaneously capture multiple data points through electronic control

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent enables continuous image acquisition by maintaining all array elements actively detecting throughout the measurement process, eliminating the intermittent nature of mechanical scanning where only one point is measured at a time

Inventive Principle:
Principle #20Continuity of useful action

3Length of stationary object

If conventional terahertz sources are used, then the device is simple, but the detectable penetration depth is limited

Engineering Contradiction:
Improvedetectable depthVSAvoidoutput power
Core Design Contradiction:
Length of stationary objectVSPower

Solution Approach 1:

The patent combines the radiation output from multiple terahertz sources in the array to achieve higher cumulative power, enabling the terahertz waves to penetrate deeper into biological tissues while maintaining system simplicity through modular array construction

Inventive Principle:
Principle #5Merging (Combining)

4Measurement precision

If conventional detectors are used, then the device structure is simple, but the detection sensitivity and signal-to-noise ratio are low

Engineering Contradiction:
Improvedetection sensitivityVSAvoiddetector structure
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent combines signals from multiple detector elements in the array to achieve higher overall detection sensitivity and signal-to-noise ratio through signal integration, while maintaining individual detector element simplicity

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent transitions from single-point detection to two-dimensional array detection, enabling simultaneous measurement across multiple spatial points and improving overall detection sensitivity through parallel signal acquisition

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This system achieves significantly larger detectable depths, faster image acquisition rates, and improved image resolution, enabling effective terahertz imaging for diagnostics in the gastrointestinal and respiratory tracts with enhanced depth and lateral resolution.

Implementation Method 1

each of the at least one terahertz source has an active area having at least one plasmonic contact electrode that can be illuminated by optical pump beams to generate the terahertz radiation

Methodology Applied
Scientific EffectPhotoconductive excitation: Photoconductivity

Implementation Method 2

each of the at least one terahertz detector has an active area having at least one plasmonic contact electrode that can be illuminated by optical pump beams to induce an output proportional to the received terahertz field

Methodology Applied
Scientific EffectPhotoconductive detection: Photoconductivity

Implementation Method 3

a laser source configured to pump the at least one terahertz source and detector using femtosecond optical beams

Methodology Applied
Scientific EffectLaser pumping: Laser

Data Source

PatentUS10863895B2Terahertz endoscopy through laser-driven terahertz sources and detectors
Publication Date: 2020.12.15 RGT UNIV OF CALIFORNIA
  • US10863895B2 patent drawing
  • US10863895B2 patent drawing
  • US10863895B2 patent drawing

AI summary

Terahertz imaging systems for endoscopy are provided. Terahertz imaging systems can be utilized in scanning tissue. Terahertz imaging systems in accordance with embodiments of the invention can include terahertz sources, terahertz detectors, and/or rotating elements. The terahertz sources can generate terahertz radiation and have plasmonic contact electrodes that can be illuminated by optical pump beams. The terahertz detectors can receive terahertz field data. The terahertz source and detector can be arranged in an array. The rotating elements can be mirror mounted at a particular angle on a micromotor. The terahertz source, rotating element, and terahertz detector can be arranged in an catheter.