Portable Terahertz Imaging System for Non-Invasive Hemorrhage Detection
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Solution Overview
Problem
Current methods for hemorrhage detection are invasive, costly, and lack sensitivity and specificity, while Alzheimer's detection is challenging due to the absence of non-invasive, cost-effective, and reliable techniques that can identify early signs effectively.
Innovation Solution
An all-fiber coupled portable terahertz imaging system that uses terahertz waves for non-invasive detection of hemorrhage and Alzheimer's, employing a miniaturized fiber-coupled terahertz system with a patch probe and femtosecond laser, capable of generating three-dimensional images with high signal-to-noise ratio, and analyzing spectral signatures for severity.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If invasive methods are used for hemorrhage detection, then detection capability is improved, but patient safety and comfort deteriorate
Solution Approach 1:
The patent replaces invasive mechanical procedures (needle insertions, surgical biopsies) with a non-invasive optical detection system using terahertz waves. The all-fiber coupled portable terahertz imaging system uses light-matter interactions to detect hemorrhage through skin and tissue without physical penetration, eliminating the harmful effects of invasive methods while maintaining detection capability.
Solution Approach 2:
The patent introduces terahertz waves as an intermediary medium to detect hemorrhage indirectly through their interaction with blood and tissue. The terahertz imaging system detects changes in tissue properties caused by hemorrhage without direct contact or invasion, using the electromagnetic waves as a mediator between the detector and the target condition.
2Measurement precision
If advanced detection systems are deployed, then detection sensitivity is improved, but system complexity and cost increase
Solution Approach 1:
The patent extracts only the essential components needed for terahertz generation and detection, eliminating unnecessary system complexity. By using an all-fiber coupled architecture, the system integrates light source, modulation, and detection functions into a compact configuration, removing bulky external components while maintaining high detection sensitivity for hemorrhage and Alzheimer's detection.
Solution Approach 2:
The patent designs a multi-functional terahertz imaging system that can detect multiple conditions (hemorrhage, Alzheimer's disease) using the same core technology platform. The all-fiber coupled portable terahertz system serves multiple diagnostic purposes, reducing the need for separate specialized equipment and thereby lowering overall system complexity and cost.
3Ease of operation
If portable systems are used, then ease of operation is improved, but measurement precision may deteriorate
Solution Approach 1:
The patent implements a nested architecture where the terahertz generation and detection components are integrated within a compact portable housing. The all-fiber coupled system nests the light source, modulators, and detectors in a hierarchical structure that maintains optical alignment and signal integrity while enabling portability. This nested design preserves measurement precision despite the reduced system size.
Solution Approach 2:
The patent combines multiple functional components (light source, terahertz generator, detector, and processing unit) into a single integrated portable device. By merging these components while maintaining their functional independence through fiber coupling, the system achieves both portability and high detection accuracy for clinical use.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The system provides early detection of hemorrhage and Alzheimer's with high sensitivity and specificity, is safe, low-cost, and portable, enabling rapid assessment in emergency situations without harmful agents or invasive procedures.
Implementation Method 1
employing a miniaturized fiber-coupled terahertz system with a patch probe and femtosecond laser
Implementation Method 2
all fiber coupled portable terahertz imaging system
Implementation Method 3
a detector module configured to: (i) receive a reflected terahertz signal from the patient
Data Source
AI summary
Method and apparatus for non-invasive condition detection using an all fiber portable terahertz imaging system. An imaging system of the present disclosure may comprise a control module comprising a femtosecond pulsed laser configured to generate an output light beam, a dispersion compensation unit configured to receive the output light beam and transmit a laser light beam generated based upon the output light beam, a beam splitter configured to receive the laser light beam and divide the laser light beam into a pump light beam and a reference light beam; and a rapid scanning optical delay line configured to receive the pump light beam and transmit an exit light beam generated based upon the pump light beam, a patch probe comprising a transmitter module, an optics lens, and a detector module.