Terpendole Natural Pesticide for Resistant Arthropod Control

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Solution Overview

Problem

The widespread use of synthetic insecticides has led to the development of resistant insect populations, necessitating the need for novel natural insecticides that can effectively control arthropod pests without the drawbacks of chemical pesticides.

Innovation Solution

The use of terpendoles, a class of indole-diterpene alkaloids produced by fungi, as a natural pesticide, applied effectively to control arthropod pests through various means such as spraying, soaking, or granule application, targeting pests like aphids, lepidopterans, and whiteflies.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If synthetic insecticides are used to control arthropod pests, then pest control effectiveness is improved, but insecticide resistance develops

Engineering Contradiction:

Improvepest control effectivenessVSAvoidinsecticide resistance

Core Design Contradiction:

ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent changes the chemical parameter from synthetic insecticides to natural terpendole compounds, fundamentally altering the chemical class being used. This parameter change allows effective pest control while avoiding the resistance issues that have developed against conventional synthetic insecticides, as pests have not been exposed to this natural compound class

Inventive Principle:

Principle #35Parameter changes

Solution Approach 2:

The patent utilizes naturally occurring terpendole compounds that can be produced by fungi and potentially sourced more sustainably than persistent synthetic chemicals. These natural compounds offer a renewable alternative that doesn't contribute to long-term resistance buildup in pest populations

Inventive Principle:

Principle #27Cheap short-living objects (Disposable)

2Reliability

If synthetic chemical insecticides are used extensively, then arthropod pest control is improved, but public and regulatory pressure increases to reduce chemical use

Engineering Contradiction:

Improvepest control effectivenessVSAvoidenvironmental and health concerns

Core Design Contradiction:

ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent substitutes chemical synthesis with natural production, replacing human-made synthetic insecticides with naturally occurring terpendole compounds produced by fungi. This substitution maintains pest control effectiveness while eliminating the environmental and health concerns associated with synthetic chemical production and application

Inventive Principle:

Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent leverages the natural production capability of fungi to generate terpendole compounds. By utilizing a biological system that naturally produces these compounds, the invention eliminates the need for complex synthetic chemical manufacturing processes and reduces the environmental footprint associated with chemical production

Inventive Principle:

Principle #25Self-service

Data Source

PatentUS11497214B2Methods of controlling pests using terpendoles

Publication Date: 2022.11.15 VALENT BIOSCIENCES CORP

AI summary

The present invention is directed to a method of controlling a pest comprising applying an effective amount of one or more terpendoles to the pest or an area in need of pest control. The present invention is further directed to a method of controlling a pest comprising applying an effective amount of one or more compounds having the following chemical structureto the pest or an area in need of pest control.