Terpene-Enriched Cannabinoid Composition for Enhanced Therapeutic Effect

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Solution Overview

Problem

Cannabis products often have low terpene content due to processing losses, which affects the functionality and bioavailability of cannabinoids, as terpenes are volatile and evaporate during drying and decarboxylation, leading to a higher relative proportion of sesquiterpenoids in processed cannabis.

Innovation Solution

A therapeutic product comprising at least one cannabinoid, one primary terpene, and a non-cannabinoid, non-terpene carrier, such as cellulose, with a terpenes to cannabinoids weight/weight ratio of 0.1 to 1.0, enhancing the therapeutic effect compared to products with the same cannabinoid amounts and half the terpene amount.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If cannabis plant material is processed through drying and decarboxylation, then cannabinoids are activated and converted to their active forms, but terpenes are lost due to evaporation, resulting in low terpene content in the final product

Engineering Contradiction:
Improvecannabinoid activationVSAvoidterpene content
Core Design Contradiction:
ReliabilityVSLoss of substance

Solution Approach 1:

The patent applies preliminary action by adding terpenes to the cannabis extract before final product formulation, ensuring terpene presence is established prior to any processing that might cause loss. This proactive approach compensates for the inevitable terpene evaporation during drying and decarboxylation steps.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent changes the concentration parameter of terpenes in the final product formulation, specifically targeting a terpene-to-cannabinoid weight ratio of 0.1 to 1.0. This parameter adjustment ensures sufficient terpene content remains after processing losses, achieving the desired therapeutic effect while accounting for evaporation during manufacturing.

Inventive Principle:
Principle #35Parameter changes

2Reliability

If terpene content is increased to enhance therapeutic effect, then bioavailability and functionality of cannabinoids improve, but product complexity and manufacturing difficulty increase

Engineering Contradiction:
Improvetherapeutic effectVSAvoidproduct composition
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent simplifies the composition by defining a specific terpene-to-cannabinoid weight ratio range (0.1 to 1.0), transforming a complex multi-component system into a controlled binary ratio system. This parameter specification makes manufacturing more manageable while ensuring therapeutic efficacy.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent creates a composite cannabinoid-terpene composition where the two components work synergistically. By defining their relationship through a specific weight ratio rather than treating them as separate additives, the invention simplifies the overall product structure while maintaining enhanced therapeutic effects.

Inventive Principle:
Principle #40Composite materials

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The product achieves an enhanced therapeutic effect for various conditions, including arthritis, pain, and mental health issues, with improved bioavailability and prolonged duration of action, using specific terpene blends and ratios.

Implementation Method 1

Being volatile agents, terpenes further evaporate during heating and decarboxylation

Methodology Applied
Scientific EffectEvaporation: Evaporation

Data Source

PatentUS11925652B2Terpene-enriched cannabinoid composition and method of treatment
Publication Date: 2024.03.12 BUZZELET DEV & TECH LTD

AI summary

A composition of at least one cannabinoid in a specific amount, and at least one primary terpene in a specific amount, where a total terpenes to total cannabinoids weight/weight ratio in the composition is from about 0.05 to about 1.0.