Test Paper Cassette Connecting Structure for Closed Pathogen Detection
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Solution Overview
Problem
Current viral pathogen detection methods are cumbersome, prone to biological pollution, and require complex operations, leading to long waiting times, high economic burdens, and increased risk of cross-infection in hospitals.
Innovation Solution
An auxiliary test paper detection device comprising a reagent cap and a test paper cassette with a connecting structure, allowing for a closed reaction system that reduces manual handling and biological contamination, enabling self-testing at home for influenza A and B viruses and other respiratory pathogens.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If manual sample transfer using pipettor or plastic straight suction pipe is used, then sample can be transferred from sample treatment device to detection device, but biological pollution is caused due to uncontrolled sample dropping and overflow
Solution Approach 1:
The patent introduces an intermediary sample transfer structure that connects the sample treatment device and detection device, enabling controlled sample transfer without direct manual handling. This intermediary mechanism prevents uncontrolled dropping and overflow, eliminating biological pollution while maintaining ease of operation.
Solution Approach 2:
The patent extracts the manual sample transfer step from the detection process by integrating the sample treatment and detection functions into a connected system. The sample transfer function is built-in through the connecting structure, removing the need for separate manual pipetting operations that cause biological pollution.
2Ease of operation
If multiple operation steps are used for sample transfer, then sample can be moved from sample treatment device to detection device, but detection process becomes complicated
Solution Approach 1:
The patent merges the sample treatment device and detection device into an integrated system through a connecting structure. This combination eliminates multiple separate operation steps for sample transfer, simplifying the detection process while maintaining functional completeness.
Solution Approach 2:
The connecting structure is pre-configured to enable automatic or semi-automatic sample transfer. The sample transfer pathway is established in advance through the connecting structure, eliminating the need for multiple manual operation steps during the detection process.
3Ease of operation
If pipettor or plastic straight suction pipe is used for sample transfer, then sample can be transferred, but inaccurate detection result is caused due to non-standard operation and inaccurate sample volume
Solution Approach 1:
The patent introduces an intermediary sample transfer mechanism within the connecting structure that ensures precise and standardized sample volume transfer. This intermediary device eliminates the variability associated with manual pipettor operation, ensuring accurate detection results while maintaining ease of use.
Solution Approach 2:
The connecting structure incorporates self-regulating sample transfer capabilities that automatically control sample volume and flow rate. The system performs the sample transfer function autonomously with built-in precision control, eliminating the need for operator skill and ensuring consistent accurate results.
4Ease of operation
If sample is transferred in open environment, then manual operation is simple, but biological pollution of environment is caused due to uncontrolled sample dropping
Solution Approach 1:
The patent introduces an intermediary enclosed sample transfer system within the connecting structure that prevents sample exposure to the external environment. The intermediary mechanism controls sample flow and contains any potential spills, eliminating environmental biological pollution while maintaining operational simplicity.
Solution Approach 2:
The connecting structure employs sealed or enclosed pathways for sample transfer, using flexible membranes or sealed channels to contain the sample throughout the transfer process. This prevents sample exposure and potential environmental contamination while allowing simple operation.
Data Source
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AI summary
An auxiliary test paper detection device includes a reagent cap and a test paper cassette. The reagent cap is used for containing a detection reagent, a sealing member is arranged at an opening of the reagent cap. The sealing member can be opened or removed under action of external force. Test paper is arranged in the test paper cassette, a sample absorption section of the test paper is exposed, an observation window is formed in the test paper cassette, and a result display area of the test paper corresponds to the observation window. A connecting structure for connecting the test paper cassette and the reagent cap is arranged between the test paper cassette and the reagent cap, and when the test paper cassette and the reagent cap are connected through the connecting structure, a closed space is formed in an inner cavity of the reagent cap. The sample absorption section of the test paper extends into the inner cavity of the reagent cap. Liquid is sub-packaged in the reagent cap in advance, and the test paper cassette and the reagent cap are connected in an insertion mode, which is simple in operation and facilitates to reduce manual operation and result errors caused by manual sample adding.