Test Platform With Printed Reference Materials for Detection Module Calibration

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Solution Overview

Problem

Existing microfluidic test apparatuses lack effective methods for quality control and correction of detection modules, leading to potential inaccuracies in biochemical reactions and analyses.

Innovation Solution

A test platform with printed reference materials and tags, including barcodes or RFID, is used to determine if correction is needed for the detection module, utilizing a light source, CCD/CMOS image sensor, and controller to compare detected results with pre-set reference values, adjusting detection conditions as necessary.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If a microfluidic test apparatus is used for biochemical reactions and analyses, then testing functionality is provided, but quality control and correction methods for detection modules are insufficient leading to potential inaccuracies

Engineering Contradiction:
Improvedetection accuracyVSAvoidquality control capability
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

The patent applies preliminary action by pre-printing reference materials with known colorimetric values onto the test platform before actual testing. This allows the detection module to be calibrated and validated against known standards, ensuring measurement precision while providing quality control capability. The reference materials serve as pre-prepared calibration targets that enable accuracy verification without requiring external calibration equipment.

Inventive Principle:
Principle #10Preliminary action

2Measurement precision

If detection module correction is implemented, then detection accuracy is improved, but additional testing procedures and reference materials are required

Engineering Contradiction:
Improvedetection accuracyVSAvoidtesting procedure complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent merges the calibration reference materials directly into the test platform structure by printing them onto the same substrate as the test chambers. This integration combines the reference standard and the test sample platform into a single device, allowing quality control and actual testing to be performed seamlessly without requiring separate calibration equipment or procedures, thus improving detection accuracy without significantly increasing procedural complexity.

Inventive Principle:
Principle #5Merging (Combining)

3Reliability

If quality control procedures are added to the test apparatus, then detection reliability is improved, but management time and operational complexity increase

Engineering Contradiction:
Improvequality control capabilityVSAvoidmanagement time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent implements self-service quality control by incorporating reference materials that enable the detection module to automatically self-calibrate and self-validate during the testing process. The system performs quality control checks autonomously by comparing detection results against the pre-printed reference values, eliminating the need for manual calibration procedures or external quality control interventions, thus improving reliability without increasing management time.

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enables efficient management of detection module performance, reduces management time, and ensures high accuracy and reliability of detection results, facilitating cost-effective and precise quality control.

Implementation Method 1

a light source, a light receiver for detecting the detection target of the microfluidic device

Methodology Applied
Scientific EffectLight emission: Light

Implementation Method 2

a light receiver configured to face the light source and to receive the light irradiated by the light source and passed through the reference material

Methodology Applied
Scientific EffectPhotoelectric detection: Photoelectric Effect

Data Source

PatentEP2698639B1Test platform, test apparatus and control method thereof
Publication Date: 2021.01.20 NEXUS DX INC
  • EP2698639B1 patent drawingFigure 1
  • EP2698639B1 patent drawingFigure 2
  • EP2698639B1 patent drawingFigure 3

AI summary

A test platform is provided for testing a detection module of a test apparatus to determine whether correction is needed or for quality control of the test apparatus. The test platform includes a body, and at least one reference material which is formed on the body and on which at least one color is printed.