Biological Test Strip Isolation Structure for Repeatability
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Solution Overview
Problem
Conventional biological test strips lack a blocking mechanism to confine the flow of reaction materials and target substances, leading to inconsistent contact with electrodes, which results in noise signals and reduced measurement repeatability, especially when dealing with non-aggregating fluids like alcohol.
Innovation Solution
A biological test strip with an isolation structure featuring a substrate, operation and auxiliary electrodes, and flow confining members, where the first flow confining member surrounds the operation electrode and the second flow confining member surrounds both the first flow confining member and the auxiliary electrode, ensuring a fixed contact area and preventing fluid overflow.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If no flow confining member is provided, then the device complexity is reduced, but the measurement precision deteriorates due to random spreading of reaction material and target substance
Solution Approach 1:
The test strip is divided into multiple functional zones using flow confining members: a first flow confining member surrounding the operation electrode and a second flow confining member surrounding the auxiliary electrode. This segmentation ensures that reaction material and target substance are confined to specific areas, preventing random spreading and ensuring consistent contact with electrodes for reliable measurements.
Solution Approach 2:
The flow confining members act as intermediary structures between the liquid sample and the electrodes. These members guide and confine the fluid flow, ensuring that the liquid contacts the electrodes through a fixed square measure area, thereby mediating the interaction to achieve consistent and repeatable measurements.
2Reliability
If flow confining members are added to confine liquid, then the measurement precision is improved, but the device complexity increases
Solution Approach 1:
The second flow confining member is positioned to surround and contain the first flow confining member, creating a nested structure. This nested arrangement of flow confining members effectively confines the liquid sample in multiple stages, ensuring consistent contact with both operation and auxiliary electrodes while maintaining a compact overall structure.
3Measurement precision
If the height of flow confining members is increased, then the liquid confinement is improved, but the ease of operation deteriorates due to increased liquid volume required
Solution Approach 1:
The flow confining members are designed with different heights at different locations: the first flow confining member has a first height and the second flow confining member has a second height greater than the first height. This local variation in height provides effective liquid confinement where needed while minimizing the overall liquid volume required, balancing measurement precision with ease of operation.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This configuration ensures consistent electron and ion exchange areas, reducing noise signals and enhancing measurement repeatability by maintaining a fixed contact area between the fluid and electrodes.
Implementation Method 1
a first flow confining member disposed on the measuring portion and surrounding the first operating end of the operation electrode; and a second flow confining member disposed on the testing portion and further surrounding the first flow confining member and the second operating end of the auxiliary electrode
Implementation Method 2
an electrode disposed on the substrate and further including an operation electrode and an auxiliary electrode... capable of preventing the liquid from contacting the electrodes with varying square measure thereof from time to time during the analyzing process
Data Source
AI summary
A biological test strip with isolation structure includes a substrate having a testing portion and a measuring portion; an electrode disposed on the substrate and including an operation electrode and an auxiliary electrode, the operation electrode having a first operating end and a first reading end, the auxiliary electrode having a second operating end and a second reading end; a first flow confining member surrounding the first operating end; and a second flow confining member surrounding the first flow confining member and the second operating end, with a height of the second flow confining member larger than a height of the first flow confining member. Therefore, the flowing scope of the dropped liquid is confined, so as to fix the square measure of the dropped liquid contacting the electrode and thereby improve the analysis repeatability.


