Texturized Resorbable Antiadhesion Membrane
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Solution Overview
Problem
Current antiadhesion surgical membranes lack flexibility and resorbability, leading to difficulties in positioning and prolonged healing times due to adhesion recurrence during surgery.
Innovation Solution
Development of an antiadhesion surgical membrane with one or both faces featuring reliefs that enhance flexibility and resorbability, created by evaporating a polymer solution such as polyethylene glycol alginate with additives like poloxamer and copper, allowing for easier placement and eventual resorption after healing.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Strength
If a solid polymer membrane is used for antiadhesion surgery, then the membrane provides structural integrity and adhesion prevention, but the membrane lacks flexibility and is difficult to position correctly
Solution Approach 1:
The membrane surface is segmented into reliefs and channels, creating a microstructured topology that maintains overall structural integrity while introducing localized flexibility zones that facilitate positioning and conformability during surgery
Solution Approach 2:
The membrane is designed as a thin film structure with controlled thickness and micro-reliefs that provide the necessary flexibility for surgical manipulation while maintaining sufficient strength to prevent tissue adhesion
2Reliability
If a non-resorbable membrane is used, then the membrane provides long-term adhesion prevention, but the membrane requires additional surgery for removal and prolongs healing time
Solution Approach 1:
The membrane is designed to be resorbable, automatically discarding itself after fulfilling its protective function during the critical healing period, thereby eliminating the need for removal surgery and reducing overall treatment time
Solution Approach 2:
The membrane transitions from a stable, functional state during surgery to a degradable state over time, dynamically adapting its properties to provide protection when needed and then being naturally absorbed after healing
3Area of stationary object
If a flat membrane surface is used, then the membrane provides complete tissue coverage, but the membrane increases contact surface area and makes movement and positioning difficult
Solution Approach 1:
The continuous membrane surface is segmented into reliefs and channels, reducing the effective contact area with tissues while maintaining overall coverage, thereby facilitating easier movement and positioning during surgical procedure
Solution Approach 2:
The membrane incorporates a porous microstructure with channels and reliefs that reduce solid-to-solid contact between the membrane and tissues, allowing for easier manipulation and positioning while still providing effective adhesion prevention
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The membrane's increased flexibility and resorbability reduce tissue adhesion, facilitate easier placement, and promote faster healing by minimizing contact surface area and promoting tissue repair with added vitamins for anti-inflammatory benefits.
Implementation Method 1
Non-stick bioadhesive membranes can be obtained by evaporating water from a solution of water and a few percent of one or more polymers
Data Source
Figure 1~3
AI summary
The membrane (1) has a planar face (2) and a texturized or jagged face (3) that includes suppling and resorbability embossments (4) or projections having a shape of small parallelepiped plots, where the membrane is made of polymer material having an alginate ester derivative. The embossments correspond to cells of a mold, where the membrane is formed by evaporation of 0.5 to 10 percentage of polymer volume and water solution in the mold.