Thaxtomin Herbicide Selective Weed Control in Rice

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Solution Overview

Problem

Current herbicides for rice cultivation are not selective and pose environmental safety concerns, leading to high costs and significant yield loss in organic rice due to the lack of effective weed control methods, especially for broadleaf and grassy weeds.

Innovation Solution

The use of thaxtomin, a cyclic dipeptide produced by Streptomyces sp., as a pre-emergence herbicide in rice growing systems, applied in various formulations to control the growth of monocotyledonous, dicotyledonous, and sedge weeds without harming rice or the environment.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If conventional herbicides are used for weed control in rice fields, then weed control effectiveness is improved, but environmental safety deteriorates and selectivity against rice is lost

Engineering Contradiction:
Improveweed control effectivenessVSAvoidenvironmental safety
Core Design Contradiction:
ProductivityVSObject-affected harmful factors

Solution Approach 1:

The patent changes the chemical parameter by using thaxtomin, a natural cyclic dipeptide product from Streptomyces sp., instead of conventional synthetic herbicides. This natural product provides selective weed control while maintaining environmental safety, resolving the contradiction between effectiveness and environmental harm.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent employs a naturally decomposable microbial product (thaxtomin) that breaks down in the environment, replacing persistent synthetic herbicides. This approach provides effective weed control while avoiding long-term environmental contamination.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

2Productivity

If selective herbicides are used for organic rice weed control, then yield loss is reduced, but availability of such herbicides is limited

Engineering Contradiction:
Improveyield protectionVSAvoidherbicide availability
Core Design Contradiction:
ProductivityVSAdaptability or versatility

Solution Approach 1:

The patent utilizes thaxtomin, a natural product produced by Streptomyces sp., which can be applied in organic rice systems. This self-service approach provides selective weed control capability specifically needed for organic agriculture, reducing yield loss without requiring conventional synthetic herbicides.

Inventive Principle:
Principle #25Self-service

3Productivity

If broadleaf and grassy weeds are controlled in organic rice, then yield loss is reduced, but control methods are limited to water management

Engineering Contradiction:
Improveyield protectionVSAvoidcontrol method complexity
Core Design Contradiction:
ProductivityVSEase of operation

Solution Approach 1:

The patent applies thaxtomin, a naturally decomposable substance produced by Streptomyces sp., as a herbicidal treatment for organic rice. This provides effective control of both broadleaf and grassy weeds that goes beyond water management alone, while maintaining simplicity suitable for organic systems.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Thaxtomin effectively controls broadleaf, sedge, and grass weeds with high selectivity to rice, reducing yield loss and environmental impact, offering a safer alternative to synthetic herbicides with excellent control rates across different weed species.

Implementation Method 1

The herbicidal mode of action is based on disruption of cell wall synthesis (Fry and Loria 2002), with inhibition of cellulose biosynthesis being the main target

Methodology Applied
Scientific EffectCell wall synthesis disruption:

Implementation Method 2

concentration of less than 1 uM of thaxtomin A causes cell swelling, necrosis and growth inhibition in mono and dicotyledonous seedlings

Methodology Applied
Scientific EffectOsmotic pressure: Osmotic Pressure

Data Source

PatentEP2418952B1Use of thaxtomin for selective control of rice and aquatic based weeds
Publication Date: 2016.11.23 MARRONE BIO INNOVATIONS INC
  • EP2418952B1 patent drawingFigure 1
  • EP2418952B1 patent drawingFigure 2
  • EP2418952B1 patent drawing

AI summary

The use of a bacterial secondary metabolite, thaxtomin is described as an effective herbicide on broadleaved, sedge and grass weeds, e.g., in rice fieIds with no phytotoxicity to rice as well as on aquatic based weeds.