Theobromine Oral Pouch Composition for Fast Sustained Release

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Solution Overview

Problem

Existing oral products containing theobromine do not provide a sufficient, fast, and sustained stimulating effect, and are not easily consumable, lacking sensory attractiveness and ease of use.

Innovation Solution

An oral product comprising a pouch with a composition containing theobromine and cocoa bean nibs as a carrier, which releases theobromine upon contact with mucosa without chewing, allowing for a fast and sustained release into the bloodstream.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If chocolate or cocoa products are used to provide theobromine, then theobromine intake is achieved, but excessive intake can cause adverse effects such as restlessness, increased heart rate, and insomnia

Engineering Contradiction:
Improvetheobromine intakeVSAvoidadverse effects
Core Design Contradiction:
Quantity of substanceVSObject-affected harmful factors

Solution Approach 1:

The patent changes the concentration parameter of theobromine in the oral composition to a specific range (0.1-10% w/w) that is sufficient to provide therapeutic effects while avoiding excessive intake that causes adverse effects. This parameter optimization resolves the contradiction between achieving adequate theobromine intake and avoiding harmful side effects.

Inventive Principle:
Principle #35Parameter changes

2Reliability

If theobromine is provided in oral compositions, then cardiovascular and respiratory benefits are achieved, but the composition must be stable and safe for consumption

Engineering Contradiction:
Improvecardiovascular and respiratory benefitsVSAvoidcomposition stability and safety
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent specifies precise parameter ranges for theobromine concentration (0.1-10% w/w) and pH value (3.0-7.0) to ensure the composition is stable, safe for consumption, and effective for cardiovascular and respiratory benefits. These parameter optimizations simultaneously achieve reliability of benefits and safety of composition.

Inventive Principle:
Principle #35Parameter changes

3Reliability

If high concentrations of theobromine are used, then therapeutic effects are enhanced, but the risk of adverse effects increases

Engineering Contradiction:
Improvetherapeutic effectsVSAvoidrisk of adverse effects
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent identifies and optimizes the optimal concentration range of theobromine (0.1-10% w/w) that maximizes therapeutic effects while minimizing the risk of adverse effects. This parameter optimization resolves the contradiction between enhancing therapeutic effects and reducing adverse effect risk.

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentEP4604746B1Oral product comprising theobromine
Publication Date: 2026.05.13 CONTRAF NICOTEX TOBACCO GMBH

AI summary

The invention relates to an oral product for delivery of at least one active ingredient comprising or consisting of - a pouch defining a cavity and - a composition comprising the at least one active ingredient and a carrier selected from the group consisting of, cocoa bean, in particular cocoa bean nibs or cocoa bean powder, coffee bean, cellulose, plant fibres, polysaccharides, oligosaccharides, polyols, and mixtures of at least two of the afore-said carriers, wherein the composition is within the cavity of the pouch and the at least one active ingredient is theobromine. The invention further relates to a method for producing an oral product.