Therapeutic Agent Delivery Device Segmentation

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Solution Overview

Problem

Existing therapeutic agent delivery devices, such as injector pens, lack ease of medication dispensing and efficient cartridge replacement, leading to inconvenience for users.

Innovation Solution

A therapeutic agent delivery device with a reusable and disposable portion design, where the disposable portion is detachably coupled to a reusable portion, featuring a syringe assembly with a needle that translates from a stowed to a deployed configuration using a compression spring and a securing mechanism for easy attachment and detachment, and an electronics assembly for controlled operation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If a disposable pen design is used, then ease of operation is improved, but loss of substance increases due to discarding the entire pen after single use

Engineering Contradiction:
Improveease of self-administrationVSAvoidwaste of medication device
Core Design Contradiction:
Ease of operationVSLoss of substance

Solution Approach 1:

The injection device is divided into two separate components: a reusable body portion containing the drive mechanism and a disposable cartridge portion containing the medication. This segmentation allows the medication to be depleted while the functional device is retained and reused, reducing waste while maintaining ease of operation.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The design enables selective discarding of only the spent cartridge portion while recovering and retaining the reusable body portion for subsequent use with fresh cartridges. This partial discarding approach eliminates the need to discard the entire device after single use.

Inventive Principle:
Principle #34Discarding and recovering

2Loss of substance

If a reusable pen design is used, then loss of substance decreases by retaining the device, but ease of operation deteriorates due to complex assembly and disassembly procedures

Engineering Contradiction:
Improveretention of medication deviceVSAvoidease of cartridge replacement
Core Design Contradiction:
Loss of substanceVSEase of operation

Solution Approach 1:

The device is segmented into modular components with standardized interfaces, allowing the cartridge to be easily attached and detached from the reusable body without complex tools or procedures, simplifying the replacement process.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The cartridge is pre-assembled with the needle and piston in a ready-to-use configuration, eliminating the need for users to perform complex assembly operations during cartridge replacement. The pre-prepared cartridge can be directly attached to the reusable body.

Inventive Principle:
Principle #10Preliminary action

3Ease of operation

If the needle remains exposed, then ease of operation is improved for quick access, but object-generated harmful factors increase due to needle exposure risks

Engineering Contradiction:
Improvequick needle accessVSAvoidneedle exposure risk
Core Design Contradiction:
Ease of operationVSObject-generated harmful factors

Solution Approach 1:

The needle is nested within the cartridge structure, allowing it to be retracted into the cartridge body when not in use. This nesting arrangement provides quick access when needed while minimizing exposure risks during storage and transport.

Inventive Principle:
Principle #7Nested doll (Nesting)

Solution Approach 2:

The cartridge design converts the potential harm of needle exposure into a benefit by providing a protective cartridge housing that contains the needle when not in use, while still allowing rapid deployment when treatment is needed.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Facilitates convenient and accurate self-administration of therapeutic agents by enabling easy replacement of spent cartridges and ensuring proper operation through the use of a secure and controlled delivery mechanism.

Implementation Method 1

A compression spring couples the housing to the cap. The compression spring biases the syringe assembly and the cap away from the deployed configuration and toward the stowed configuration.

Methodology Applied
Scientific EffectElastic potential energy: Spring

Data Source

PatentUS20240342389A1Therapeutic agent delivery device
Publication Date: 2024.10.17 ELI LILLY & CO
  • US20240342389A1 patent drawing
  • US20240342389A1 patent drawing
  • US20240342389A1 patent drawing

AI summary

A therapeutic agent delivery device includes a disposable portion and a reusable portion that detachably carries the disposable portion. The reusable portion includes a drive mechanism having a guide, a rotary actuator, and a follower drivably coupled to the rotary actuator and movably coupled to the guide. The rotary actuator is actuatable to rotatably drive the follower, and the follower thereby follows the guide and translates the drive mechanism. The drive mechanism thereby translates a syringe assembly of the disposable portion from a stowed configuration to a deployed configuration.