Thermoacoustic SAR Estimation for MRI Safety

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Solution Overview

Problem

Current methods for estimating the specific absorption rate (SAR) of tissue regions during magnetic resonance imaging (MRI) scans are inadequate, particularly with increasing field strengths, as they fail to accurately predict local heating effects and are impractical due to temperature resolution limitations and interference issues with parallel transmit technology.

Innovation Solution

A method and system that radiate tissue regions with short pulses to generate thermoacoustic signals, which are then used to calculate and scale temperature rises, estimating the SAR before an MRI scan, allowing for adjustments to scanner parameters to ensure safety.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Illumination intensity

If MR imaging scanners utilize parallel transmit technology with multiple channels controlled independently, then image signal-to-noise ratio and contrast are improved, but strong local heating effects occur due to constructive interference leading to high local SAR

Engineering Contradiction:
Improveimage signal-to-noise ratioVSAvoidlocal heating effects
Core Design Contradiction:
Illumination intensityVSObject-affected harmful factors

Solution Approach 1:

The patent performs preliminary SAR estimation using ultrasonic thermometry before the actual MR imaging scan. By calculating the predicted temperature rise from the planned RF pulse sequence in advance, the system can identify potential local heating issues before they occur, allowing for preventive adjustment of transmit parameters to avoid constructive interference effects.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system implements a feedback mechanism where the estimated SAR and predicted temperature rise are used to adjust the RF transmit parameters. The measured temperature distribution from ultrasonic thermometry is fed back to modify the parallel transmit channel amplitudes and phases, preventing excessive local SAR while maintaining image quality.

Inventive Principle:
Principle #23Feedback

2Loss of information

If MR imaging thermometry is used to monitor temperature, then temperature information is obtained, but the temperature resolution of approximately 1 degree Celsius is insufficient given that the upper limit value of temperature rise is set to 1 degree Celsius

Engineering Contradiction:
Improvetemperature informationVSAvoidtemperature resolution
Core Design Contradiction:
Loss of informationVSMeasurement precision

Solution Approach 1:

The patent introduces ultrasonic thermometry as an intermediary measurement technique. Instead of relying on MR imaging thermometry with insufficient resolution, the system uses ultrasonic waves as a mediator to detect temperature changes through speed of sound variations, achieving sub-degree Celsius precision required for safe MR imaging monitoring.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent replaces the MR imaging-based temperature measurement system with an ultrasonic thermometry system. By substituting the magnetic resonance measurement mechanism with ultrasonic wave propagation measurements, the system achieves the necessary temperature resolution without the limitations of MR thermometry.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Illumination intensity

If increasing field strengths are utilized for MR imaging, then image signal-to-noise ratio and contrast are improved, but SAR values and spatial variation of local SAR increase resulting in higher risk of tissue heating

Engineering Contradiction:
Improveimage signal-to-noise ratioVSAvoidSAR values
Core Design Contradiction:
Illumination intensityVSPower

Solution Approach 1:

Before high-field MR imaging scans, the system performs preliminary SAR estimation using ultrasonic thermometry to predict temperature rises. This advance calculation allows identification of high-SAR regions before actual RF irradiation, enabling pre-adjustment of transmit parameters to maintain image quality while reducing SAR exposure.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system dynamically adjusts RF transmit parameters based on the estimated SAR distribution. By changing the amplitudes, phases, and frequencies of the parallel transmit channels according to the predicted temperature map, the system optimizes the balance between image signal-to-noise ratio and SAR reduction for high-field imaging.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach provides a more accurate estimation of SAR, reducing the risk of local heating and improving MRI safety by allowing for parameter adjustments based on precise SAR calculations, even with high field strengths and complex SAR patterns.

Implementation Method 1

radiating the tissue region with a plurality of short pulses, wherein the tissue region emits thermoacoustic signals responsive to the short pulses

Methodology Applied
Scientific EffectElectromagnetic absorption: Absorption (EM radiation)

Implementation Method 2

the tissue region emits thermoacoustic signals responsive to the short pulses

Methodology Applied
Scientific EffectThermoacoustic effect: Thermoacoustic Effect

Implementation Method 3

receiving the thermoacoustic signals by at least one ultrasonic transducer

Methodology Applied
Scientific EffectPiezoelectric effect: Piezoelectric Effect

Data Source

PatentUS10016147B2Method and system for estimating the specific absorption rate of a tissue region prior to a magnetic resonance imaging scan
Publication Date: 2018.07.10 ENDRA LIFE SCIENCES INC
  • US10016147B2 patent drawing
  • US10016147B2 patent drawing
  • US10016147B2 patent drawing

AI summary

A method and system for estimating a specific absorption rate of a tissue region prior to performing a magnetic resonance (MR) imaging scan on the tissue region. The method comprises radiating the tissue region with a plurality of short pulses, wherein the tissue region emits thermoacoustic signals responsive to the short pulses, receiving the thermoacoustic signals by at least one ultrasonic transducer, calculating a temperature rise of the tissue region based on the received thermoacoustic signals, scaling the temperature rise to estimate a temperature rise of the tissue region resulting from an MR imaging scan, and estimating the specific absorption rate of the tissue region based on the estimated temperature rise.